电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

SNF8 抗体 (N-Term)

This anti-SNF8 antibody is a 兔 多克隆 antibody detecting SNF8 in WB 和 IHC. Suitable for 人, 大鼠, 小鼠, Cow, 犬, 豚鼠, 马, 兔 和 斑马鱼.
产品编号 ABIN2777341
发货至: 中国

Quick Overview for SNF8 抗体 (N-Term) (ABIN2777341)

抗原

See all SNF8 抗体
SNF8 (Vacuolar-sorting Protein SNF8 (SNF8))

适用

  • 35
  • 26
  • 11
  • 7
  • 7
  • 6
  • 6
  • 6
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 1
人, 大鼠, 小鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼

宿主

  • 47
  • 2

克隆类型

  • 48
  • 2
多克隆

标记

  • 22
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This SNF8 antibody is un-conjugated

应用范围

  • 23
  • 18
  • 13
  • 13
  • 5
  • 4
  • 3
  • 2
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

    • 15
    • 8
    • 6
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    序列

    MHRRGVGAGA IAKKKLAEAK YKERGTVLAE DQLAQMSKQL DMFKTNLEEF

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

    产品特性

    This is a rabbit polyclonal antibody against SNF8. It was validated on Western Blot and immunohistochemistry.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human EAP30
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 258 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    SNF8 (Vacuolar-sorting Protein SNF8 (SNF8))

    别名

    EAP30

    背景

    ELL encodes an RNA polymerase II transcription factor that undergoes frequent translocation in acute myeloid leukemia (AML). In addition to its elongation activity, ELL contains a novel type of RNA polymerase II interaction domain that is capable of repressing polymerase activity in promoter-specific transcription. EAP30 is a subunit of the ELL complex. EAP30 can interact with ELL and derepress ELL's inhibitory activity in vitro.SNF8, VPS25 (MIM 610907), and VPS36 (MIM 610903) form ESCRT-II (endosomal sorting complex required for transport II), a complex involved in endocytosis of ubiquitinated membrane proteins. SNF8, VPS25, and VPS36 are also associated in a multiprotein complex with RNA polymerase II elongation factor (ELL, MIM 600284) (Slagsvold et al., 2005 [PubMed 15755741], Kamura et al., 2001 [PubMed 11278625]).[supplied by OMIM].
    Alias Symbols: Dot3, EAP30, VPS22
    Protein Interaction Partner: GOLGA2, VPS25, TRIM54, VAC14, UBC, BCAT1, SUV39H2, ACBD3, DUS3L, WDR12, PRMT6, RPUSD2, KDM1A, EFTUD2, TTC1, HARS, GTF2F1, GTF2E1, ELL, RBP1, MCM2, ADORA1, METTL14, NUDCD3, RILP, VPS36, CHMP6, VPS28, SNF8, TSG101, VPS20, NIF3L1, DVL2,
    Protein Size: 258

    分子量

    29 kDa

    基因ID

    11267

    NCBI登录号

    NM_007241, NP_009172

    UniProt

    Q96H20
You are here:
Chat with us!