OLIG2 抗体 (N-Term)
Quick Overview for OLIG2 抗体 (N-Term) (ABIN2777314)
抗原
See all OLIG2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- MDSDASLVSS RPSSPEPDDL FLPARSKGSS GSAFTGGTVS SSTPSDCPPE
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预测反应
- Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 85%
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产品特性
- This is a rabbit polyclonal antibody against OLIG2. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human OLIG2
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 323 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Expression of oligodendrocyte-associated genes in dorsolateral prefrontal cortex of patients with schizophrenia." in: Schizophrenia research, Vol. 98, Issue 1-3, pp. 129-38, (2007) (PubMed).
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Expression of oligodendrocyte-associated genes in dorsolateral prefrontal cortex of patients with schizophrenia." in: Schizophrenia research, Vol. 98, Issue 1-3, pp. 129-38, (2007) (PubMed).
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- OLIG2 (Oligodendrocyte Lineage Transcription Factor 2 (OLIG2))
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别名
- OLIG2
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背景
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OLIG2 is a basic helix-loop-helix transcription factor which is expressed in oligodendroglial tumors of the brain. OLIG2 is an essential regulator of ventral neuroectodermal progenitor cell fate. It is associated with T-cell acute lymphoblastic leukemia due to a chromosomal translocation t(14,21)(q11.2,q22). OLIG2 might play a role in learning deficits associated with Down syndrome.This gene encodes a basic helix-loop-helix transcription factor which is expressed in oligodendroglial tumors of the brain. The protein is an essential regulator of ventral neuroectodermal progenitor cell fate. The gene is involved in a chromosomal translocation t(14,21)(q11.2,q22) associated with T-cell acute lymphoblastic leukemia. Its chromosomal location is within a region of chromosome 21 which has been suggested to play a role in learning deficits associated with Down syndrome. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: BHLHB1, OLIGO2, PRKCBP2, RACK17, bHLHe19
Protein Interaction Partner: CUL3, SRRM1, SOX8, NKX2-2, EP300, SOX10,
Protein Size: 323 -
分子量
- 32 kDa
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基因ID
- 10215
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NCBI登录号
- NM_005806, NP_005797
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UniProt
- Q13516
抗原
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