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YAF2 抗体 (Middle Region)

This 兔 多克隆 antibody specifically detects YAF2 in WB 和 IHC. It exhibits reactivity toward 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马 和 兔.
产品编号 ABIN2777311
发货至: 中国
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Quick Overview for YAF2 抗体 (Middle Region) (ABIN2777311)

抗原

See all YAF2 抗体
YAF2 (YY1 Associated Factor 2 (YAF2))

适用

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人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔

宿主

  • 24
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克隆类型

  • 25
多克隆

标记

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This YAF2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    Middle Region

    序列

    KGTSTRKPRP VSQLVAQQVT QQFVPPTQSK KEKKDKVEKE KSEKETTSKK

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 86%, Rabbit: 100%, Rat: 100%

    产品特性

    This is a rabbit polyclonal antibody against YAF2. It was validated on Western Blot and immunohistochemistry.

    纯化方法

    Protein A purified

    免疫原

    The immunogen is a synthetic peptide directed towards the middle region of human YAF2
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 180 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    YAF2 (YY1 Associated Factor 2 (YAF2))

    别名

    YAF2

    背景

    YAF2 interacts with YY1, a zinc finger protein involved in negative regulation of muscle-restricted genes. YAF2 contains a single N-terminal C2-X10-C2 zinc finger, and in contrast to YY1, is up-regulated during myogenic differentiation. It also facilitates proteolytic cleavage of YY1 by the calcium- activated protease, m-calpain, suggesting a mechanism by which this protein antagonizes the negative effect of YY1.The protein encoded by this gene interacts with YY1, a zinc finger protein involved in negative regulation of muscle-restricted genes. This gene product itself contains a single N-terminal C2-X10-C2 zinc finger, and in contrast to YY1, is up-regulated during myogenic differentiation. It also facilitates proteolytic cleavage of YY1 by the calcium- activated protease, m-calpain, suggesting a mechanism by which this protein antagonizes the negative effect of YY1. Multiple transcript variants encoding different isoforms have been found for this gene, but the full-length nature of only two have been confirmed to date.
    Alias Symbols: MGC41856
    Protein Interaction Partner: SETBP1, XAGE1E, RING1, RNF2, BMI1, GABPB1, CSNK2A2, UBC, CAND1, PCGF1, KDM2B, PCGF5, PCGF6, L3MBTL2, FBRS, BCORL1, BCOR, MGA, CBX3, WDR5, PCGF3, YAF2, USP7, PCGF2, TFDP1, SKP1, HDAC2, E2F6, CSNK2A1, ZFP42, YY1, MYCN,
    Protein Size: 180

    分子量

    20 kDa

    基因ID

    10138

    NCBI登录号

    NM_005748, NP_005739

    UniProt

    Q8IY57
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