HOXA5 抗体 (Middle Region)
Quick Overview for HOXA5 抗体 (Middle Region) (ABIN2777305)
抗原
See all HOXA5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- VGTASGAEED APASSEQASA QSEPSPAPPA QPQIYPWMRK LHISHDNIGG
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预测反应
- Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 93%
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产品特性
- This is a rabbit polyclonal antibody against HOXA5. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human HOXA5
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 270 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "The histone chaperone NAP1L3 is required for haematopoietic stem cell maintenance and differentiation." in: Scientific reports, Vol. 8, Issue 1, pp. 11202, (2019) (PubMed).
: "Partial functional redundancy between Hoxa5 and Hoxb5 paralog genes during lung morphogenesis." in: American journal of physiology. Lung cellular and molecular physiology, Vol. 304, Issue 12, pp. L817-30, (2013) (PubMed).
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: "The histone chaperone NAP1L3 is required for haematopoietic stem cell maintenance and differentiation." in: Scientific reports, Vol. 8, Issue 1, pp. 11202, (2019) (PubMed).
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- HOXA5 (Homeobox A5 (HOXA5))
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别名
- HOXA5
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背景
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In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. Methylation of this gene may result in the loss of its expression and, since the encoded protein upregulates the tumor suppressor p53, this protein may play an important role in tumorigenesis.
Alias Symbols: HOX1, HOX1.3, HOX1C, MGC9376
Protein Interaction Partner: PRMT6, TWIST1, UBC, ELAVL1, SOX2, ZNF408, GTF2A1L, SMAD1, DDIT3, PBX1, MEIS1, FOXA2, CDX4, FOXO1,
Protein Size: 270 -
分子量
- 29 kDa
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基因ID
- 3202
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NCBI登录号
- NM_019102, NP_061975
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UniProt
- Q6FG31
抗原
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