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HOXB5 抗体 (N-Term)

This anti-HOXB5 antibody is a 兔 多克隆 antibody detecting HOXB5 in WB 和 IHC. Suitable for 人, 小鼠, 大鼠, 犬, Cow, 马, 兔 和 豚鼠. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN2777303
发货至: 中国

Quick Overview for HOXB5 抗体 (N-Term) (ABIN2777303)

抗原

See all HOXB5 抗体
HOXB5 (Homeobox B5 (HOXB5))

适用

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人, 小鼠, 大鼠, 犬, Cow, 马, 兔, 豚鼠

宿主

  • 48
  • 5

克隆类型

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多克隆

标记

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This HOXB5 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    N-Term

    序列

    MSSYFVNSFS GRYPNGPDYQ LLNYGSGSSL SGSYRDPAAM HTGSYGYNYN

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

    产品特性

    This is a rabbit polyclonal antibody against HOXB5. It was validated on Western Blot and immunohistochemistry.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human HOXB5
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 269 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Fu, Lui, Sham, Cheung, Tam: "HOXB5 expression is spatially and temporarily regulated in human embryonic gut during neural crest cell colonization and differentiation of enteric neuroblasts." in: Developmental dynamics : an official publication of the American Association of Anatomists, Vol. 228, Issue 1, pp. 1-10, (2003) (PubMed).

  • 抗原

    HOXB5 (Homeobox B5 (HOXB5))

    别名

    HOXB5

    背景

    HOXB5 belongs to the homeobox family. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXB genes located in a cluster on chromosome 17. The exact role of this gene has yet to be determined.This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in lung and gut development. Increased expression of this gene is associated with a distinct biologic subset of acute myeloid leukemia (AML) and the occurrence of bronchopulmonary sequestration (BPS) and congenital cystic adenomatoid malformation (CCAM) tissue.
    Alias Symbols: HHO.C10, HOX2, HOX2A, HU-1, Hox2.1
    Protein Interaction Partner: MAGEA11, CTBP2, CTBP1, TRIM23, UBC,
    Protein Size: 269

    分子量

    30 kDa

    基因ID

    3215

    NCBI登录号

    NM_002147, NP_002138

    UniProt

    P09067
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