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POU1F1 抗体 (C-Term)

Cited in 1 publication. This 兔 多克隆 anti-POU1F1 antibody specifically detects POU1F1 in WB 和 IHC. The antibody is reactive with 人, 小鼠, 大鼠, 犬, Cow, 山羊, 马, 兔, 绵羊, 豚鼠 和 斑马鱼 samples.
产品编号 ABIN2777285
发货至: 中国
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Quick Overview for POU1F1 抗体 (C-Term) (ABIN2777285)

抗原

See all POU1F1 抗体
POU1F1 (POU Class 1 Homeobox 1 (POU1F1))

适用

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人, 小鼠, 大鼠, 犬, Cow, 山羊, 马, 兔, 绵羊, 豚鼠, 斑马鱼

宿主

  • 7

克隆类型

  • 7
多克隆

标记

  • 7
This POU1F1 antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

    • 2
    • 1
    • 1
    C-Term

    序列

    QEIMRMAEEL NLEKEVVRVW FCNRRQREKR VKTSLNQSLF SISKEHLECR

    预测反应

    Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 86%

    产品特性

    This is a rabbit polyclonal antibody against POU1F1. It was validated on Western Blot and immunohistochemistry.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the C terminal region of human POU1F1
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 291 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Tennant, Gottlieb: "HIF prolyl hydroxylase-3 mediates alpha-ketoglutarate-induced apoptosis and tumor suppression." in: Journal of molecular medicine (Berlin, Germany), Vol. 88, Issue 8, pp. 839-49, (2010) (PubMed).

  • 抗原

    POU1F1 (POU Class 1 Homeobox 1 (POU1F1))

    别名

    POU1F1

    背景

    PIT1 is a pituitary-specific transcription factor responsible for pituitary development and hormone expression in mammals and is a member of the POU family of transcription factors that regulate mammalian development. The POU family is so named because the first 3 members identified were PIT1 and OCT1 of mammals, and Unc-86 of C. elegans. PIT1 contains 2 protein domains, termed POU-specific and POU-homeo, which are both necessary for high affinity DNA binding on genes encoding growth hormone and prolactin. PIT1 is also important for regulation of the genes encoding prolactin and thyroid-stimulating hormone beta subunit by thyrotropin-releasing hormone and cyclic AMP.
    Alias Symbols: PIT1, CPHD1, GHF-1, Pit-1, POU1F1a
    Protein Interaction Partner: CEBPD, NCOR1, CREBBP, MED1, GATA2, NR1I3, NR1I2, PITX1, JUN, ETS1, NR3C1, VDR, PPARG, PPARA,
    Protein Size: 291

    分子量

    33 kDa

    基因ID

    5449

    NCBI登录号

    NM_000306, NP_000297

    UniProt

    P28069

    途径

    Regulation of Carbohydrate Metabolic Process
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