我们推荐在您的浏览器上开启Javascript，以获得最佳效果。

MXI1 抗体 (Middle Region)

Name: MXI1 抗体 (Middle Region)
SKU: ABIN2777278
Availability: OutOfStock

This anti-MXI1 antibody is a 兔多克隆 antibody detecting MXI1 in WB. Suitable for 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 兔, 斑马鱼, 马和 Saccharomyces cerevisiae.

Host: Mouse Target Name: MXI1 Sample Tissue: Mouse Testis Antibody Dilution: 1ug/ml (MXI1 抗体 (Middle Region))

WB Suggested Anti-MXI1 Antibody Titration: 0. (MXI1 抗体 (Middle Region))

2 images

产品编号 ABIN2777278

发货至: 中国

Quick Overview for MXI1 抗体 (Middle Region) (ABIN2777278)

抗原

See all MXI1 抗体

MXI1 (MAX Interactor 1 (MXI1))

适用

人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 兔, 斑马鱼, 马, Saccharomyces cerevisiae

宿主

兔

克隆类型

多克隆

标记

This MXI1 antibody is un-conjugated

应用范围

Western Blotting (WB)

Discover our top product MXI1 Primary Antibody

抗原表位
8

5

2

2

2

2

2

1

1

1

1

1

1

1

1
Middle Region

序列

QGPQEMERIR MDSIGSTISS DRSDSEREEI EVDVESTEFS HGEVDNISTT

预测反应

Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 79%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 90%, Zebrafish: 77%

产品特性

This is a rabbit polyclonal antibody against MXI1. It was validated on Western Blot using a cell lysate as a positive control.

纯化方法

Affinity Purified

免疫原

The immunogen is a synthetic peptide directed towards the middle region of human MXI1
anti-MAX Interactor 1 (MXI1) (AA 1-182) antibody
MXI1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1B10 unconjugated

anti-MAX Interactor 1 (MXI1) (Middle Region) antibody
MXI1 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 兔, 斑马鱼, Saccharomyces cerevisiae WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-MAX Interactor 1 (MXI1) (AA 73-182) antibody
MXI1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1F3 unconjugated

anti-MAX Interactor 1 (MXI1) (N-Term) antibody
MXI1 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, Pig WB 宿主: 兔 Polyclonal unconjugated

anti-MAX Interactor 1 (MXI1) (AA 75-173) antibody
MXI1 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-MAX Interactor 1 (MXI1) (N-Term) antibody
MXI1 适用: 人, 小鼠 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-MAX Interactor 1 (MXI1) (AA 176-225) antibody
MXI1 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 兔, 斑马鱼, Pig, Bat, Hamster, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-MAX Interactor 1 (MXI1) (AA 215-264) antibody
MXI1 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 兔, 斑马鱼, Pig, Bat, Hamster, 猴, 小鸡 WB 宿主: 兔 Polyclonal unconjugated

anti-MAX Interactor 1 (MXI1) (AA 170-295) antibody
MXI1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

anti-MAX Interactor 1 (MXI1) (AA 76-295) antibody
MXI1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

应用备注

Optimal working dilutions should be determined experimentally by the investigator.

说明

Antigen size: 295 AA

限制

仅限研究用
状态

Liquid

浓度

Lot specific

缓冲液

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freeze-thaw cycles.

储存条件

-20 °C

储存方法

For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
抗原

MXI1 (MAX Interactor 1 (MXI1))

别名

MXI1

背景

Expression of the c-myc gene, which produces an oncogenic transcription factor, is tightly regulated in normal cells but is frequently deregulated in human cancers. The MXI1 gene encodes a transcriptional repressor protein thought to negatively regulate MYC function, and is therefore a potential tumor suppressor. This protein inhibits the transcriptional activity of MYC by competing for MAX, another basic helix-loop-helix protein that binds to MYC and is required for its function. Defects in MXI1 are frequently found in patients with prostate tumors. Expression of the c-myc gene, which produces an oncogenic transcription factor, is tightly regulated in normal cells but is frequently deregulated in human cancers. The protein encoded by this gene is a transcriptional repressor thought to negatively regulate MYC function, and is therefore a potential tumor suppressor. This protein inhibits the transcriptional activity of MYC by competing for MAX, another basic helix-loop-helix protein that binds to MYC and is required for its function. Defects in this gene are frequently found in patients with prostate tumors. Three alternatively spliced transcripts encoding different isoforms have been described. Additional alternatively spliced transcripts may exist but the products of these transcripts have not been verified experimentally.
Alias Symbols: MAD2, MGC43220, MXD2, MXI, bHLHc11
Protein Interaction Partner: NOTCH2NL, KRTAP10-3, KRTAP10-8, KRTAP10-5, KRTAP10-9, KRTAP10-7, KRT40, RPL23AP32, CALCOCO2, MAX, ENTPD5, UBC, APP, CDC20, BUB1B, SIN3B, SIN3A, SMC3, MYC,
Protein Size: 295

分子量

33 kDa

基因ID

4601

NCBI登录号

NM_130439, NP_569157

途径

Maintenance of Protein Location