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NFYA 抗体 (C-Term)

This anti-NFYA antibody is a 兔 多克隆 antibody detecting NFYA in WB 和 IHC. Suitable for 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔 和 Saccharomyces cerevisiae.
产品编号 ABIN2777243
发货至: 中国

Quick Overview for NFYA 抗体 (C-Term) (ABIN2777243)

抗原

See all NFYA 抗体
NFYA (Nuclear Transcription Factor Y, alpha (NFYA))

适用

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  • 1
人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔, Saccharomyces cerevisiae

宿主

  • 27

克隆类型

  • 25
  • 2
多克隆

标记

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This NFYA antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

    • 7
    • 3
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    • 1
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    • 1
    C-Term

    序列

    YLHESRHRHA MARKRGEGGR FFSPKEKDSP HMQDPNQADE EAMTQIIRVS

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 80%

    产品特性

    This is a rabbit polyclonal antibody against NFYA. It was validated on Western Blot and immunohistochemistry.

    纯化方法

    Protein A purified

    免疫原

    The immunogen is a synthetic peptide directed towards the C terminal region of human NFYA
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 347 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    NFYA (Nuclear Transcription Factor Y, alpha (NFYA))

    别名

    NFYA

    背景

    NFYA is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds to CCAAT motifs in the promoter regions in a variety of genes. Subunit A associates with a tight dimer composed of the B and C subunits, resulting in a trimer that binds to DNA with high specificity and affinity. The sequence specific interactions of the complex are made by the A subunit, suggesting a role as the regulatory subunit. In addition, there is evidence of post-transcriptional regulation in this gene product, either by protein degradation or control of translation. Further regulation is represented by alternative splicing in the glutamine-rich activation domain, with clear tissue-specific preferences for the two isoforms.
    Alias Symbols: HAP2, CBF-A, CBF-B, NF-YA
    Protein Interaction Partner: LUC7L2, POGZ, NFYB, GTF2A1, CSNK2A1, UBC, APPBP2, TP63, TP53, NFYC, EP300, CDK2, CCNA2, CDC25A, APP, RPS6KA6, JUN, HDAC1, ATF2, SP1, TAF6, TAF11, TAF12, PAPOLG, PWP1, SREBF2, ZHX2, ZHX1, ZHX3, KPNB1, SRSF1, HMGA1, SRF, USF2, USF1, NFYA, NR5A1, POU2F1, CEB
    Protein Size: 347

    分子量

    37 kDa

    基因ID

    4800

    NCBI登录号

    NM_002505, NP_002496

    UniProt

    P23511

    途径

    Regulation of Lipid Metabolism by PPARalpha
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