NFE2 抗体 (N-Term)
Our Local Distributor
北京 101111
Quick Overview for NFE2 抗体 (N-Term) (ABIN2777230)
抗原
See all NFE2 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- N-Term
-
原理
- NFE2 Antibody - N-terminal region
-
序列
- MSPCPPQQSR NRVIQLSTSE LGEMELTWQE IMSITELQGL NAPSEPSFEP
-
预测反应
- Cow: 92%, Guinea Pig: 87%, Horse: 87%, Human: 100%, Mouse: 77%, Rat: 92%
-
产品特性
- This is a rabbit polyclonal antibody against NFE2. It was validated on Western Blot.
-
纯化方法
- Affinity Purified
-
免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human NFE2
-
-
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
说明
-
We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP31217-100UG
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 0.5 mg/mL
-
缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- prevent freeze-thaw cycles
-
储存条件
- 4 °C,-20 °C
-
储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
-
-
- NFE2 (Nuclear Factor (Erythroid-Derived 2), 45kDa (NFE2))
-
别名
- NFE2
-
背景
-
Background Information: NFE2 is a component of the NF-E2 complex essential for regulating erythroid and megakaryocytic maturation and differentiation. NFE2 binds to the hypersensitive site 2 (HS2) of the beta-globin control region (LCR). This subunit (NFE2) recognizes the TCAT/C sequence of the AP-1-like core palindrome present in a number of erythroid and megakaryocytic gene promoters. NFE2 is requires MAFK or other small MAF proteins for binding to the NF-E2 motif. NFE2 may play a role in all aspects of hemoglobin production from globin and heme synthesis to procurement of iron.
Gene Name: Nuclear factor (erythroid-derived 2), 45 kDa
Alternative Symbols: p45, NF-E2
Protein Name: Transcription factor NF-E2 45 kDa subunit
-
分子量
- 41kDa
-
基因ID
- 4778
-
NCBI登录号
- NP_006154
-
UniProt
- Q16621
抗原
-