NFE2 抗体 (N-Term)
Quick Overview for NFE2 抗体 (N-Term) (ABIN2777230)
抗原
See all NFE2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- MSPCPPQQSR NRVIQLSTSE LGEMELTWQE IMSITELQGL NAPSEPSFEP
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预测反应
- Cow: 92%, Guinea Pig: 87%, Horse: 87%, Human: 100%, Mouse: 77%, Rat: 92%
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产品特性
- This is a rabbit polyclonal antibody against NFE2. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human NFE2
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 373 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- NFE2 (Nuclear Factor (Erythroid-Derived 2), 45kDa (NFE2))
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别名
- NFE2
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背景
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NFE2 is a component of the NF-E2 complex essential for regulating erythroid and megakaryocytic maturation and differentiation. NFE2 binds to the hypersensitive site 2 (HS2) of the beta-globin control region (LCR). This subunit (NFE2) recognizes the TCAT/C sequence of the AP-1-like core palindrome present in a number of erythroid and megakaryocytic gene promoters. NFE2 is requires MAFK or other small MAF proteins for binding to the NF-E2 motif. NFE2 may play a role in all aspects of hemoglobin production from globin and heme synthesis to procurement of iron.
Alias Symbols: NF-E2, p45
Protein Interaction Partner: BTRC, NFE2L3, NFE2L2, NFE2, ATF4, Dlg4, TXN, ITCH, Yap1, Nedd4, WWP1, MAPK8, KAT2B, SCAND1, SSX5, HMGN1, ELF5, PHYHIP, MAFF, MAFG, PEX14, MAFK, CREBBP,
Protein Size: 373 -
分子量
- 41 kDa
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基因ID
- 4778
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NCBI登录号
- NM_006163, NP_006154
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UniProt
- Q16621
抗原
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