NFE2 抗体 (C-Term)
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北京 101111
Quick Overview for NFE2 抗体 (C-Term) (ABIN2777229)
抗原
See all NFE2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- Nfe2 Antibody - C-terminal region
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序列
- ARGEADRTLE VMRQQLAELY HDIFQHLRDE SGNSYSPEEY VLQQAADGAI
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预测反应
- Cow: 86%, Dog: 93%, Guinea Pig: 93%, Horse: 79%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%
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产品特性
- This is a rabbit polyclonal antibody against Nfe2. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C-terminal region of MOUSE Nfe2
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP31216-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- NFE2 (Nuclear Factor (Erythroid-Derived 2), 45kDa (NFE2))
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别名
- Nfe2
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背景
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Background Information: Nfe2 is a component of the NF-E2 complex essential for regulating erythroid and megakaryocytic maturation and differentiation.It binds to the hypersensitive site 2 (HS2) of the beta-globin control region (LCR). This subunit (NFE2) recognizes the TCAT/C sequence of the AP-1-like core palindrome present in a number of erythroid and megakaryocytic gene promoters. It requires MAFK or other small MAF proteins for binding to the NF-E2 motif. It may play a role in all aspects of hemoglobin production from globin and heme synthesis to procurement of iron.
Gene Name: nuclear factor (erythroid-derived 2), 45 kDa
Alternative Symbols: p4, p45, NF-E, NF-E2, p45NF, p45nf-, p45NFE2, p45nf-e2, NF-E2/P45
Protein Name: Transcription factor NF-E2 45 kDa subunit
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分子量
- 41kDa
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基因ID
- 18022
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NCBI登录号
- NP_032711
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UniProt
- Q07279
抗原
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