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IRF9 抗体 (N-Term)

Cited in 2+ publications. This 兔 多克隆 anti-IRF9 antibody specifically detects IRF9 in WB 和 IHC. The antibody is reactive with 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔 和 斑马鱼 samples.
产品编号 ABIN2777226
发货至: 中国
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Quick Overview for IRF9 抗体 (N-Term) (ABIN2777226)

抗原

See all IRF9 抗体
IRF9 (Interferon Regulatory Factor 9 (IRF9))

适用

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人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼

宿主

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克隆类型

  • 45
  • 14
多克隆

标记

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This IRF9 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    N-Term

    序列

    PWKHAGKQDF REDQDAAFFK AWAIFKGKYK EGDTGGPAVW KTRLRCALNK

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

    产品特性

    This is a rabbit polyclonal antibody against ISGF3G. It was validated on Western Blot and immunohistochemistry.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human ISGF3G
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 393 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Bidwell, Slaney, Withana, Forster, Cao, Loi, Andrews, Mikeska, Mangan, Samarajiwa, de Weerd, Gould, Argani, Möller, Smyth, Anderson, Hertzog, Parker: "Silencing of Irf7 pathways in breast cancer cells promotes bone metastasis through immune escape." in: Nature medicine, Vol. 18, Issue 8, pp. 1224-31, (2013) (PubMed).

    Schumacher, Lau, Johnson: "Structural basis of core promoter recognition in a primitive eukaryote." in: Cell, Vol. 115, Issue 4, pp. 413-24, (2003) (PubMed).

  • 抗原

    IRF9 (Interferon Regulatory Factor 9 (IRF9))

    别名

    ISGF3G

    背景

    ISGF3G functions to recruit RNA polymerase II to the promoter of interferon-stimulated genes and requires histone deacetylases. Defects in ISGF3 can cause resistance to IFN-.(2a) treatment.
    Alias Symbols: IRF-9, ISGF3, ISGF3G, p48
    Protein Interaction Partner: S100A13, MYO1F, TOP1, IRF1, IRF2BP1, DNMT3A, ELAVL1, STAT2, IFNAR2, CREBBP, DACH2, DMRTC2, TLX3, VENTX, ARID3B, NR2E3, POU2F1, HOXC9, TLX2, STAT1, IFNA1, RELA, NFKB1,
    Protein Size: 393

    分子量

    44 kDa

    基因ID

    10379

    NCBI登录号

    NM_006084, NP_006075

    UniProt

    Q00978

    途径

    JAK/STAT Signaling, Interferon-gamma Pathway, Hepatitis C
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