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NFIL3 抗体 (Middle Region)

This 兔 多克隆 anti-NFIL3 antibody specifically detects NFIL3 in WB. The antibody is reactive with 人, 小鼠, 大鼠, Cow, 绵羊, 犬, 豚鼠, 马, 斑马鱼 和 兔 samples.
产品编号 ABIN2777219
发货至: 中国
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Quick Overview for NFIL3 抗体 (Middle Region) (ABIN2777219)

抗原

See all NFIL3 抗体
NFIL3 (Nuclear Factor, Interleukin 3 Regulated (NFIL3))

适用

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人, 小鼠, 大鼠, Cow, 绵羊, 犬, 豚鼠, 马, 斑马鱼, 兔

宿主

  • 35
  • 1
  • 1

克隆类型

  • 37
多克隆

标记

  • 25
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This NFIL3 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

    • 9
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    Middle Region

    序列

    GYSHSPPLLQ VNRSSSNSPR TSETDDGVVG KSSDGEDEQQ VPKGPIHSPV

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Sheep: 100%, Zebrafish: 85%

    产品特性

    This is a rabbit polyclonal antibody against NFIL3. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the middle region of human NFIL3
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 462 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    NFIL3 (Nuclear Factor, Interleukin 3 Regulated (NFIL3))

    别名

    NFIL3

    背景

    NFIL3 is a basic leucine zipper (bZIP) transcription factor that represses or activates transcription in non-osteoblastic cells. NFIL3 play a role in attenuation of PTH target gene transcription in osteoblasts. NFIL3 repression domain interacts specifically with the TBP binding repressor protein Dr1.Glucocorticoid-mediated upregulation of the bZIP transcriptional repressor gene, NFIL3, is dependent on [Ca2+]i levels, and correlates with Glucocorticoid-evoked apoptosis of Glucocorticoid-sensitive CEM-C7-14 cells. NFIL3 is involved in a distinct growth factor-regulated signaling pathway that is responsible for the survival of early B-cell progenitors, and whose alteration by E2A-HLF leads to childhood B lineage leukemia.
    Alias Symbols: E4BP4, IL3BP1, NF-IL3A, NFIL3A
    Protein Interaction Partner: AMOTL2, TRAF2, MAFF, BATF, NFIL3, MAFG, DDIT3, CBX8, SUMO2, UBC, CREB3, DR1,
    Protein Size: 462

    分子量

    51 kDa

    基因ID

    4783

    NCBI登录号

    NM_005384, NP_005375

    UniProt

    Q16649
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