E2F4 抗体 (C-Term)
Quick Overview for E2F4 抗体 (C-Term) (ABIN2777218)
抗原
See all E2F4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- SSELLEELMS SEVFAPLLRL SPPPGDHDYI YNLDESEGVC DLFDVPVLNL
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
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产品特性
- This is a rabbit polyclonal antibody against E2F4. It was validated on Western Blot and immunohistochemistry.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human E2F4
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anti-E2F Transcription Factor 4, P107/p130-Binding (E2F4) antibody
E2F4 适用: 人, 小鼠, 大鼠 ELISA, WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-E2F Transcription Factor 4, P107/p130-Binding (E2F4) antibodyE2F4 适用: 人, 小鼠, 大鼠, 猴 ELISA, WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-E2F Transcription Factor 4, P107/p130-Binding (E2F4) (AA 211-301) antibodyE2F4 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 5B7 unconjugated
anti-E2F Transcription Factor 4, P107/p130-Binding (E2F4) (AA 106-144), (N-Term) antibodyE2F4 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-E2F Transcription Factor 4, P107/p130-Binding (E2F4) (acLys96) antibodyE2F4 适用: 人 ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-E2F Transcription Factor 4, P107/p130-Binding (E2F4) (AA 160-299) antibodyE2F4 适用: 人 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-E2F Transcription Factor 4, P107/p130-Binding (E2F4) antibodyE2F4 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-E2F Transcription Factor 4, P107/p130-Binding (E2F4) (C-Term) antibodyE2F4 适用: 人, 小鼠, 大鼠, Cow, 马, 兔, 小鸡, 犬, Pig, 猴, 豚鼠, 斑马鱼, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-E2F Transcription Factor 4, P107/p130-Binding (E2F4) (acLys96) antibodyE2F4 适用: 人, 小鼠, 大鼠 ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-E2F Transcription Factor 4, P107/p130-Binding (E2F4) (AA 1-413) antibodyE2F4 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 413 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- E2F4 (E2F Transcription Factor 4, P107/p130-Binding (E2F4))
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别名
- E2F4
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背景
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The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins. It is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein binds to all three of the tumor suppressor proteins pRB, p107 and p130, but with higher affinity to the last two. It also plays an important role in the suppression of proliferation-associated genes, and its gene mutation and increased expression may be associated with human cancer.
Alias Symbols: E2F-4
Protein Interaction Partner: RBL2, TFDP1, RBL1, RB1, XPO1, PCM1, HDAC1, POLR1D, CHMP2A, AP3S2, TRIM28, LIN9, ARID3A, NCOR2, HDAC3, AR, CEBPA, LIN54, LIN37, UBC, ATAD2, SIN3A, ASH2L, HCFC1, TRRAP, KAT2A, ID2, E2F1, KMT2A, ID3, SMAD3, NOLC1, TFDP2, NDN, SMAD2, BRCA1, RYBP, RNF144A, FHL
Protein Size: 413 -
分子量
- 44 kDa
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基因ID
- 1874
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NCBI登录号
- NM_001950, NP_001941
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UniProt
- Q16254
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途径
- Cell Division Cycle, Mitotic G1-G1/S Phases, Regulation of Cell Size
抗原
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