HNF1A 抗体 (C-Term)
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Quick Overview for HNF1A 抗体 (C-Term) (ABIN2777209)
抗原
See all HNF1A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- QTMLITDTTN LSALASLTPT KQVFTSDTEA SSESGLHTPA SQATTLHVPS
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 85%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against HNF1A. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C-terminal region of human HNF1A
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeat freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- HNF1A (HNF1 Homeobox A (HNF1A))
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别名
- HNF1A
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背景
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The protein encoded by this gene is a transcription factor required for the expression of several liver-specific genes. The encoded protein functions as a homodimer and binds to the inverted palindrome 5'-GTTAATNATTAAC-3'. Defects in this gene are a cause of maturity onset diabetes of the young type 3 (MODY3) and also can result in the appearance of hepatic adenomas. Alternative splicing results in multiple transcript variants encoding different isoforms.
Alias Symbols: HNF1, LFB1, TCF1, MODY3, TCF-1, HNF-1A, IDDM20
Protein Size: 452 -
分子量
- 49 kDa
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基因ID
- 6927
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NCBI登录号
- NM_000545, NP_000536
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UniProt
- P20823
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途径
- Hormone Transport, Carbohydrate Homeostasis
抗原
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