WT1 抗体 (N-Term)
Our Local Distributor
北京 101111
Quick Overview for WT1 抗体 (N-Term) (ABIN2777189)
抗原
See all WT1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- N-Term
-
序列
- DFAPPGASAY GSLGGPAPPP APPPPPPPPP HSFIKQEPSW GGAEPHEEQC
-
预测反应
- Dog: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%
-
产品特性
- This is a rabbit polyclonal antibody against WT1. It was validated on Western Blot.
-
纯化方法
- Affinity Purified
-
免疫原
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human WT1
-
-
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeat freeze-thaw cycles.
-
储存条件
- -20 °C
-
储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
-
- WT1 (Wilms Tumor 1 (WT1))
-
别名
- WT1
-
背景
-
WT1 is a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the normal development of the urogenital system, and it is mutated in a small subset of patients with Wilm's tumors. Multiple transcript variants, resulting from alternative splicing at two coding exons, have been well characterized. There is also evidence for the use of non-AUG (CUG) translation initiation site upstream of, and in-frame with the first AUG, leading to additional isoforms.
Protein Interaction Partner: KRTAP10-3, KRTAP10-8, KRT40, EGR1, MDM2, DVL3, CIAO1, TP53, HSPA4, TAOK1, NPM3, ZNF205, SUZ12, MEN1, EZH2, DNMT1, WTIP, WTAP, PAWR, UBE2I, TP63, FHL2, TP73, PRKACA, CREBBP, U2AF2, PAX2, AREG,
Protein Size: 432 -
分子量
- 47 kDa
-
基因ID
- 7490
-
途径
- Tube Formation
抗原
-