TNNT1 抗体 (Middle Region)
Quick Overview for TNNT1 抗体 (Middle Region) (ABIN2777153)
抗原
See all TNNT1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- WIHQLESEKF DLMAKLKQQK YEINVLYNRI SHAQKFRKGA GKGRVGGRWK
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 85%
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产品特性
- This is a rabbit polyclonal antibody against TNNT1. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human TNNT1
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anti-Slow Skeletal Troponin T (TNNT1) (AA 1-261) antibody
TNNT1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Slow Skeletal Troponin T (TNNT1) (AA 1-259) antibodyTNNT1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Slow Skeletal Troponin T (TNNT1) antibodyTNNT1 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Slow Skeletal Troponin T (TNNT1) (AA 1-251) antibodyTNNT1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Slow Skeletal Troponin T (TNNT1) (AA 1-228) antibodyTNNT1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Slow Skeletal Troponin T (TNNT1) (Internal Region) antibodyVerified TNNT1 适用: 人 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Slow Skeletal Troponin T (TNNT1) (AA 1-251) antibodyTNNT1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Slow Skeletal Troponin T (TNNT1) (N-Term) antibodyTNNT1 适用: 人, 小鼠, 大鼠 WB, ICC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Slow Skeletal Troponin T (TNNT1) (C-Term) antibodyTNNT1 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Slow Skeletal Troponin T (TNNT1) (AA 1-262) antibodyTNNT1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 278 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- TNNT1 (Slow Skeletal Troponin T (TNNT1))
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别名
- TNNT1
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背景
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TNNT1 is a protein that is a subunit of troponin, which is a regulatory complex located on the thin filament of the sarcomere. This complex regulates striated muscle contraction in response to fluctuations in intracellular calcium concentration. This complex is composed of three subunits: troponin C, which binds calcium, troponin T, which binds tropomyosin, and troponin I, which is an inhibitory subunit. This protein is the slow skeletal troponin T subunit. Mutations in this gene cause nemaline myopathy type 5, also known as Amish nemaline myopathy, a neuromuscular disorder characterized by muscle weakness and rod-shaped, or nemaline, inclusions in skeletal muscle fibers which affects infants, resulting in death due to respiratory insufficiency, usually in the second year.This gene encodes a protein that is a subunit of troponin, which is a regulatory complex located on the thin filament of the sarcomere. This complex regulates striated muscle contraction in response to fluctuations in intracellular calcium concentration. This complex is composed of three subunits: troponin C, which binds calcium, troponin T, which binds tropomyosin, and troponin I, which is an inhibitory subunit. This protein is the slow skeletal troponin T subunit. Mutations in this gene cause nemaline myopathy type 5, also known as Amish nemaline myopathy, a neuromuscular disorder characterized by muscle weakness and rod-shaped, or nemaline, inclusions in skeletal muscle fibers which affects infants, resulting in death due to respiratory insufficiency, usually in the second year. Multiple transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: ANM, MGC104241, TNT, STNT, TNTS
Protein Interaction Partner: CCDC136, TFIP11, LDOC1, MORF4L1, TBPL1, TPM3, TPM1, TNNT1, NFE2L2, KRT40, UBC, PI4KA, SERPINA4, OSM, MARS, HSP90AB1, FYN, EEF1G, DDX5, CHD3, BLOC1S2, C2orf44, ZNF768, ZNF250, ZC3H15, NAGK, HMP19, TRA2A, TMEM98, ARMC8, OSBP2, ZKSCAN5, LARP1, NACAD, SNW1, S
Protein Size: 278 -
分子量
- 33 kDa
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基因ID
- 7138
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NCBI登录号
- NM_003283, NP_003274
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UniProt
- P13805
抗原
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