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TNNI1 抗体 (N-Term)

This anti-TNNI1 antibody is a 兔 多克隆 antibody detecting TNNI1 in WB 和 IHC. Suitable for 人, 大鼠, 小鼠, Cow, 犬, 山羊, 豚鼠, 马 和 兔. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN2777151
发货至: 中国

Quick Overview for TNNI1 抗体 (N-Term) (ABIN2777151)

抗原

See all TNNI1 抗体
TNNI1 (Slow Skeletal Troponin I (TNNI1))

适用

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  • 1
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人, 大鼠, 小鼠, Cow, 犬, 山羊, 豚鼠, 马, 兔

宿主

  • 42
  • 18
  • 1

克隆类型

  • 42
  • 19
多克隆

标记

  • 39
  • 12
  • 9
  • 1
This TNNI1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

    • 18
    • 6
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    • 1
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    N-Term

    序列

    MPEVERKPKI TASRKLLLKS LMLAKAKECW EQEHEEREAE KVRYLAERIP

    预测反应

    Cow: 93%, Dog: 93%, Goat: 79%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%

    产品特性

    This is a rabbit polyclonal antibody against TNNI1. It was validated on Western Blot and immunohistochemistry.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human TNNI1
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 187 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Salzler, Shah, Doré, Bauerlein, Miloscio, Latres, Papadopoulos, Olson, MacDonald, Duan: "Myostatin deficiency but not anti-myostatin blockade induces marked proteomic changes in mouse skeletal muscle." in: Proteomics, Vol. 16, Issue 14, pp. 2019-27, (2016) (PubMed).

  • 抗原

    TNNI1 (Slow Skeletal Troponin I (TNNI1))

    别名

    TNNI1

    背景

    Troponin proteins associate with tropomyosin and regulate the calcium sensitivity of the myofibril contractile apparatus of striated muscles. Each troponin-tropomyosin complex contains 1 Molecule from each of the 3 troponins: T, C, and I. The troponin I (TNI) subfamily contains three genes: TNI-skeletal-fast-twitch, TNI-skeletal-slow-twitch, and TNI-cardiac. TNNI1 prevents muscle contraction by inhibiting calcium-mediated conformational changes in actin-myosin complexes.
    Alias Symbols: DKFZp451O223, TNN1, SSTNI
    Protein Interaction Partner: PNMA1, MDFI, TRIM63, TRIM55, TNNC1, TNNT2, EIF3I, CCDC85B, TNNT1, ACTA1, PKD2L1,
    Protein Size: 187

    分子量

    21 kDa

    基因ID

    7135

    NCBI登录号

    NM_003281, NP_003272

    UniProt

    P19237
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