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MMP3 抗体 (Middle Region)

This anti-MMP3 antibody is a 兔 多克隆 antibody detecting MMP3 in WB 和 IHC. Suitable for 人, 大鼠, 小鼠, 兔, Pig, Cow, 犬 和 马. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN2777122
发货至: 中国

Quick Overview for MMP3 抗体 (Middle Region) (ABIN2777122)

抗原

See all MMP3 抗体
MMP3 (Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase) (MMP3))

适用

  • 200
  • 62
  • 57
  • 21
  • 7
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  • 5
  • 4
  • 4
  • 1
  • 1
  • 1
  • 1
  • 1
人, 大鼠, 小鼠, 兔, Pig, Cow, 犬, 马

宿主

  • 143
  • 101
  • 2
  • 2
  • 2
  • 1

克隆类型

  • 126
  • 125
多克隆

标记

  • 144
  • 18
  • 12
  • 7
  • 6
  • 6
  • 6
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  • 6
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  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This MMP3 antibody is un-conjugated

应用范围

  • 167
  • 131
  • 60
  • 60
  • 52
  • 32
  • 30
  • 29
  • 13
  • 13
  • 13
  • 8
  • 7
  • 5
  • 5
  • 3
  • 2
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

    • 30
    • 24
    • 15
    • 10
    • 9
    • 9
    • 8
    • 8
    • 7
    • 7
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region

    序列

    AEDFPGIDSK IDAVFEEFGF FYFFTGSSQL EFDPNAKKVT HTLKSNSWLN

    预测反应

    Cow: 93%, Dog: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 93%, Rat: 93%

    产品特性

    This is a rabbit polyclonal antibody against MMP3. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the middle region of human MMP3
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 477 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Stickel, Osterreicher, Halangk, Berg, Homann, Hellerbrand, Patsenker, Schneider, Kolb, Friess, Schuppan, Puhl, Seitz, Leathart, Day: "No role of matrixmetalloproteinase-3 genetic promoter polymorphism 1171 as a risk factor for cirrhosis in alcoholic liver disease." in: Alcoholism, clinical and experimental research, Vol. 32, Issue 6, pp. 959-65, (2008) (PubMed).

  • 抗原

    MMP3 (Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase) (MMP3))

    别名

    MMP3

    背景

    MMP3 can degrade fibronectin, laminin, gelatins of type I, III, IV, and V, collagens III, IV, X, and IX, and cartilage proteoglycans. MMP3 activates procollagenase.Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades fibronectin, laminin, collagens III, IV, IX, and X, and cartilage proteoglycans. The enzyme is thought to be involved in wound repair, progression of atherosclerosis, and tumor initiation. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: MGC126102, MGC126103, MGC126104, MMP-3, SL-1, STMY, STMY1, STR1, CHDS6
    Protein Interaction Partner: MEOX2, SPOCK3, SPOCK1, TNFSF11, CCL8, CCL13, BCAN, TIMP1, TIMP3, MMP3, SERPINE1, PLG, SPP1, CCL7, CCL2, ACAN, IGFBP3, DCN, HAPLN1,
    Protein Size: 477

    分子量

    43 kDa

    基因ID

    4314

    NCBI登录号

    NM_002422, NP_002413

    UniProt

    P08254
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