Cytokeratin 13 抗体 (C-Term)
Quick Overview for Cytokeratin 13 抗体 (C-Term) (ABIN2777115)
抗原
See all Cytokeratin 13 (KRT13) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- EAQLSELRSE MECQNQEYKM LLDIKTRLEQ EIATYRSLLE GQDAKKRQPP
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 83%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 92%, Zebrafish: 85%
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产品特性
- This is a rabbit polyclonal antibody against KRT13. It was validated on Western Blot and immunohistochemistry.
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纯化方法
- Protein A purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human KRT13
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 420 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Cytokeratin 13 (KRT13) (Keratin 13 (KRT13))
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别名
- KRT13
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背景
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KRT13 is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Most of the type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. This type I cytokeratin is paired with keratin 4 and expressed in the suprabasal layers of non-cornified stratified epithelia.The protein encoded by this gene is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Most of the type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. This type I cytokeratin is paired with keratin 4 and expressed in the suprabasal layers of non-cornified stratified epithelia. Mutations in this gene and keratin 4 have been associated with the autosomal dominant disorder White Sponge Nevus. The type I cytokeratins are clustered in a region of chromosome 17q21.2. Alternative splicing of this gene results in multiple transcript variants, however, not all variants have been described.
Alias Symbols: CK13, K13, MGC161462, MGC3781
Protein Interaction Partner: FAM127C, GOLGA8EP, KRT79, TRIM42, KRT6C, CEP57L1, TXLNA, PPP1R18, ALS2CR11, KLC3, C1orf216, CCDC101, KRT71, IFT20, KLC4, FBF1, ANKRD36BP1, LSM2, EXOSC5, C1orf109, CCHCR1, KRT20, AMOTL2, ABI3, BLOC1S6, FARS2, ABI2, CEP57, EIF4E2, TSG101, TMSB4X, PSMB2, PSM
Protein Size: 420 -
分子量
- 46 kDa
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基因ID
- 3860
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NCBI登录号
- NM_002274, NP_002265
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UniProt
- P13646
抗原
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