Glucagon 抗体 (N-Term)
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北京 101111
Quick Overview for Glucagon 抗体 (N-Term) (ABIN2777107)
抗原
See all Glucagon (GCG) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- GCG Antibody - N-terminal region
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序列
- LSDPDQMNED KRHSQGTFTS DYSKYLDSRR AQDFVQWLMN TKRNRNNIAK
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 75%
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产品特性
- This is a rabbit polyclonal antibody against GCG. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Protein A purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human GCG
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anti-Glucagon (GCG) (AA 119-148), (C-Term) antibody
GCG 适用: 人 WB, IF, FACS, IHC (p) 宿主: 兔 Polyclonal RB19525 unconjugated
anti-Glucagon (GCG) antibodyGCG 适用: 人 WB, IHC, ELISA, IF, FM 宿主: 兔 Polyclonal unconjugated
anti-Glucagon (GCG) (AA 21-180) antibodyGCG 适用: 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Glucagon (GCG) antibodyGCG 适用: 人 IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-Glucagon (GCG) (AA 25-54), (N-Term) antibodyGCG 适用: 人, 小鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB19443 unconjugated
anti-Glucagon (GCG) (AA 1-180) antibodyGCG 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1E2-E6 unconjugated
anti-Glucagon (GCG) (N-Term) antibodyGCG 适用: 人, 大鼠, 小鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Glucagon (GCG) (AA 53-81) antibodyGCG 适用: 人 IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Glucagon (GCG) antibodyGCG 适用: 人 ELISA 宿主: 小鼠 Monoclonal 2F9 unconjugated
anti-Glucagon (GCG) antibodyGCG 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal 24GB2965 unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP42010-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1.0 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- Glucagon (GCG)
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别名
- GCG
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背景
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Background Information: GCG is actually a preproprotein that is cleaved into four distinct mature peptides. One of these, glucagon, is a pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis. Glucagon is a ligand for a specific G-protein linked receptor whose signalling pathway controls cell proliferation. Two of the other peptides are secreted from gut endocrine cells and promote nutrient absorption through distinct mechanisms. Finally, the fourth peptide is similar to glicentin, an active enteroglucagon.The protein encoded by this gene is actually a preproprotein that is cleaved into four distinct mature peptides. One of these, glucagon, is a pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis. Glucagon is a ligand for a specific G-protein linked receptor whose signalling pathway controls cell proliferation. Two of the other peptides are secreted from gut endocrine cells and promote nutrient absorption through distinct mechanisms. Finally, the fourth peptide is similar to glicentin, an active enteroglucagon.
Gene Name: Glucagon
Alternative Symbols: GLP1, GLP2, GRPP, GLP-1
Protein Name: Glucagon
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分子量
- 20kDa
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基因ID
- 2641
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NCBI登录号
- NP_002045
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UniProt
- P01275
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途径
- Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, cAMP Metabolic Process, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Negative Regulation of intrinsic apoptotic Signaling
抗原
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