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DLAT 抗体 (N-Term)

This anti-DLAT antibody is a 兔 多克隆 antibody detecting DLAT in WB 和 IHC. Suitable for 人, 小鼠, 大鼠, 兔, 犬, 斑马鱼, Cow, 豚鼠 和 马.
产品编号 ABIN2777101
发货至: 中国

Quick Overview for DLAT 抗体 (N-Term) (ABIN2777101)

抗原

See all DLAT 抗体
DLAT (Dihydrolipoyl Transacetylase (DLAT))

适用

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人, 小鼠, 大鼠, 兔, 犬, 斑马鱼, Cow, 豚鼠, 马

宿主

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克隆类型

  • 60
  • 9
多克隆

标记

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This DLAT antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    N-Term

    序列

    WTPSSGATPR NRLLLQLLGS PGRRYYSLPP HQKVPLPSLS PTMQAGTIAR

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

    产品特性

    This is a rabbit polyclonal antibody against DLAT. It was validated on Western Blot and immunohistochemistry.

    纯化方法

    Protein A purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human DLAT
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 647 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    DLAT (Dihydrolipoyl Transacetylase (DLAT))

    别名

    DLAT

    背景

    DLAT is dihydrolipoamide acetyltransferase, the E2 subunit of the mammalian pyruvate dehydrogenase complex of the inner mitochondrial membrane. Patients with primary biliary cirrhosis show autoantibodies to DLAT.The DLAT gene encodes dihydrolipoamide acetyltransferase (EC 2.3.1.12), the E2 subunit of the mammalian pyruvate dehydrogenase complex (PDC, EC 1.2.4.1) of the inner mitochondrial membrane. Patients with primary biliary cirrhosis (PBC, MIM 109720) show autoantibodies to DLAT.[supplied by OMIM].
    Alias Symbols: DLTA, PDC-E2, PDCE2
    Protein Interaction Partner: MDM2, UBC, ADRB2, PRKD3, PDHX, MMGT1, MRPL1, ACAD9, SYNCRIP, PDHA2, PDHA1, OGDH, NDUFS4, HSPA1L, DLD, COX5B, COPS5, CUL1, SIRT7, TSG101, KIAA0101, PSMA3, PDK4, PDK3, PDK2, PDK1, PDHB,
    Protein Size: 647

    分子量

    69 kDa

    基因ID

    1737

    NCBI登录号

    NM_001931, NP_001922

    UniProt

    P10515
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