APCS 抗体 (N-Term)
(1 reference)Quick Overview for APCS 抗体 (N-Term) (ABIN2777091)
抗原
See all APCS 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- NFTLCFRAYS DLSRAYSLFS YNTQGRDNEL LVYKERVGEY SLYIGRHKVT
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预测反应
- Guinea Pig: 86%, Human: 100%, Mouse: 77%, Rat: 93%
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产品特性
- This is a rabbit polyclonal antibody against APCS. It was validated on Western Blot and immunohistochemistry.
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纯化方法
- Protein A purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human APCS
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anti-Amyloid P Component, Serum (APCS) (AA 23-223) antibody
APCS 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Amyloid P Component, Serum (APCS) (AA 22-222) antibodyAPCS 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Amyloid P Component, Serum (APCS) (AA 1-223) antibodyAPCS 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Amyloid P Component, Serum (APCS) (AA 143-223) antibodyAPCS 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal APCS-3240 unconjugated
anti-Amyloid P Component, Serum (APCS) (AA 35-149) antibodyAPCS 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4F3 unconjugated
anti-Amyloid P Component, Serum (APCS) (AA 117-223) antibodyAPCS 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Amyloid P Component, Serum (APCS) antibodyAPCS 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Amyloid P Component, Serum (APCS) antibodyAPCS 适用: 人 WB, IF 宿主: 小鼠 Monoclonal 5A9 unconjugated
anti-Amyloid P Component, Serum (APCS) (AA 117-223) antibodyAPCS 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4E8 unconjugated
anti-Amyloid P Component, Serum (APCS) (Internal Region) antibodyAPCS 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 223 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Activation of human microglia by fibrillar prion protein-related peptides is enhanced by amyloid-associated factors SAP and C1q." in: Neurobiology of disease, Vol. 19, Issue 1-2, pp. 273-82, (2005) (PubMed).
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: "Activation of human microglia by fibrillar prion protein-related peptides is enhanced by amyloid-associated factors SAP and C1q." in: Neurobiology of disease, Vol. 19, Issue 1-2, pp. 273-82, (2005) (PubMed).
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- APCS (Amyloid P Component, Serum (APCS))
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别名
- APCS
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背景
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APCS is a glycoprotein, belonging to the pentraxin family of proteins, which has a characteristic pentameric organization. These family members have considerable sequence homology which is thought to be the result of gene duplication. The binding of the protein to proteins in the pathological amyloid cross-beta fold suggests its possible role as a chaperone. This protein is also thought to control the degradation of chromatin. It has been demonstrated that this protein binds to apoptotic cells at an early stage, which raises the possibility that it is involved in dealing with apoptotic cells in vivo.The protein encoded by this gene is a glycoprotein, belonging to the pentraxin family of proteins, which has a characteristic pentameric organization. These family members have considerable sequence homology which is thought to be the result of gene duplication. The binding of the encoded protein to proteins in the pathological amyloid cross-beta fold suggests its possible role as a chaperone. This protein is also thought to control the degradation of chromatin. It has been demonstrated that this protein binds to apoptotic cells at an early stage, which raises the possibility that it is involved in dealing with apoptotic cells in vivo. This gene has multiple polyadenylation sites.
Alias Symbols: MGC88159, PTX2, SAP
Protein Interaction Partner: COPS5, GK, HES1, GRB2, GOT2, FCGR3B, FCGR2B, CALU, TG, LAMA1, FCGR1A, FCGR3A, FN1, CRP, C4BPA, C1QA, COL4A1, APCS,
Protein Size: 223 -
分子量
- 25 kDa
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基因ID
- 325
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NCBI登录号
- NM_001639, NP_001630
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UniProt
- P02743
抗原
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