CXCR2 抗体 (N-Term)
Quick Overview for CXCR2 抗体 (N-Term) (ABIN502194)
抗原
See all CXCR2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- MEDFNMESDS FEDFWKGEDL SNYSYSSTLP PFLLDAAPCE PESLEINKYF
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预测反应
- Human: 100%
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产品特性
- This is a rabbit polyclonal antibody against IL8RB. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human IL8RB
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anti-Chemokine (C-X-C Motif) Receptor 2 (CXCR2) antibody
CXCR2 适用: 人 ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 5F7A11 unconjugated
anti-Chemokine (C-X-C Motif) Receptor 2 (CXCR2) (AA 316-360) antibodyCXCR2 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Receptor 2 (CXCR2) (pSer347) antibodyCXCR2 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Receptor 2 (CXCR2) antibodyCXCR2 适用: 人 ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 7E9H12 unconjugated
anti-Chemokine (C-X-C Motif) Receptor 2 (CXCR2) (AA 1-40) antibodyCXCR2 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Receptor 2 (CXCR2) (N-Term) antibodyCXCR2 适用: 人 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Receptor 2 (CXCR2) (AA 1-57) antibodyCXCR2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Receptor 2 (CXCR2) (Extracellular Domain) antibodyCXCR2 适用: 人, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Receptor 2 (CXCR2) (AA 1-30), (N-Term) antibodyCXCR2 适用: 人 WB, IHC, FACS 宿主: 兔 Chimeric SE2 unconjugated Recombinant Antibody
anti-Chemokine (C-X-C Motif) Receptor 2 (CXCR2) (C-Term) antibodyCXCR2 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 360 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- CXCR2 (Chemokine (C-X-C Motif) Receptor 2 (CXCR2))
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别名
- IL8RB
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背景
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IL8RB is the receptor for interleukin-8 which is a powerful neutrophil chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. IL8RB binds to IL-8 with high affinity. IL8RB also binds with high affinity to CXCL3, GRO/MGSA and NAP-2.The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. This receptor also binds to chemokine (C-X-C motif) ligand 1 (CXCL1/MGSA), a protein with melanoma growth stimulating activity, and has been shown to be a major component required for serum-dependent melanoma cell growth. This receptor mediates neutrophil migration to sites of inflammation. The angiogenic effects of IL8 in intestinal microvascular endothelial cells are found to be mediated by this receptor. Knockout studies in mice suggested that this receptor controls the positioning of oligodendrocyte precursors in developing spinal cord by arresting their migration. This gene, IL8RA, a gene encoding another high affinity IL8 receptor, as well as IL8RBP, a pseudogene of IL8RB, form a gene cluster in a region mapped to chromosome 2q33-q36. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CD182, CDw128b, CMKAR2, CXCR2, IL8R2, IL8RA, IL8RB
Protein Interaction Partner: ST13, RAB11FIP2, CXCL5, PPP2CA, MYO5B, PPBP, GNA14, RGS12, GPRASP1, CXCL1, CXCL8, CXCR1, CXCR2, GNAI3, GNAI2, GNA15, CXCL3, CXCL2, CXCL6, GRIA1, ARRB1, ADRA1A, GTF3A,
Protein Size: 360 -
分子量
- 41 kDa
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基因ID
- 3579
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NCBI登录号
- NM_001557, NP_001548
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UniProt
- P25025
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途径
- cAMP Metabolic Process
抗原
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