ALOX15B 抗体 (C-Term)
Quick Overview for ALOX15B 抗体 (C-Term) (ABIN2777053)
抗原
See all ALOX15B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- ATCEGFIATL PPVNATCDVI LALWLLSKEP GDQRPLGTYP DEHFTEEAPR
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预测反应
- Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%
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产品特性
- This is a rabbit polyclonal antibody against ALOX15B. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Protein A purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human ALOX15B
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 676 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Inverse relationship between 15-lipoxygenase-2 and PPAR-gamma gene expression in normal epithelia compared with tumor epithelia." in: Neoplasia (New York, N.Y.), Vol. 7, Issue 3, pp. 280-93, (2005) (PubMed).
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: "Inverse relationship between 15-lipoxygenase-2 and PPAR-gamma gene expression in normal epithelia compared with tumor epithelia." in: Neoplasia (New York, N.Y.), Vol. 7, Issue 3, pp. 280-93, (2005) (PubMed).
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- ALOX15B (Arachidonate 15-Lipoxygenase B (ALOX15B))
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别名
- ALOX15B
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背景
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ALOX15B is a member of the lipoxygenase family of structurally related nonheme iron dioxygenases involved in the production of fatty acid hydroperoxides. The protein converts arachidonic acid exclusively to 15S-hydroperoxyeicosatetraenoic acid, while metabolizing linoleic acid less effectively.This gene encodes a member of the lipoxygenase family of structurally related nonheme iron dioxygenases involved in the production of fatty acid hydroperoxides. The encoded protein converts arachidonic acid exclusively to 15S-hydroperoxyeicosatetraenoic acid, while metabolizing linoleic acid less effectively. This gene is located in a cluster of related genes and a pseudogene that spans approximately 100 kilobases on the short arm of chromosome 17. Alternatively spliced transcript variants encoding different isoforms have been described.
Alias Symbols: 15-LOX-2
Protein Interaction Partner: RXRA, PPARG, ERAL1,
Protein Size: 676 -
分子量
- 74 kDa
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基因ID
- 247
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NCBI登录号
- NM_001141, NP_001132
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UniProt
- O15296
抗原
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