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TSH receptor 抗体 (C-Term)

This anti-TSH receptor antibody is a 兔 多克隆 antibody detecting TSH receptor in WB. Suitable for 人, 小鼠, 大鼠, 犬, 兔, 绵羊, Cow, 马 和 豚鼠. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN2777037
发货至: 中国

Quick Overview for TSH receptor 抗体 (C-Term) (ABIN2777037)

抗原

See all TSH receptor (TSHR) 抗体
TSH receptor (TSHR) (Thyroid Stimulating Hormone Receptor (TSHR))

适用

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人, 小鼠, 大鼠, 犬, 兔, 绵羊, Cow, 马, 豚鼠

宿主

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克隆类型

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多克隆

标记

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This TSH receptor antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    C-Term

    序列

    KLDAVYLNKN KYLTVIDKDA FGGVYSGPSL LLPLGRKSLS FETQKAPRSS

    预测反应

    Cow: 83%, Dog: 93%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 86%, Rabbit: 86%, Rat: 93%, Sheep: 79%

    产品特性

    This is a rabbit polyclonal antibody against TSHR. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the C terminal region of human TSHR
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 253 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Pessina, Castillo, Sartore, Borrego, Meikle: "Semiquantitative immunohistochemical marker staining and localization in canine thyroid carcinoma and normal thyroid gland." in: Veterinary and comparative oncology, (2014) (PubMed).

  • 抗原

    TSH receptor (TSHR) (Thyroid Stimulating Hormone Receptor (TSHR))

    别名

    TSHR

    背景

    TSHR is receptor for thyrothropin. It plays a central role in controlling thyroid cell metabolism. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. It also acts as a receptor for thyrostimulin (GPA2+GPB5).
    Alias Symbols: LGR3, MGC75129, hTSHR-I, CHNG1
    Protein Interaction Partner: ADRB2, SCRIB, UBC, TSHB, RABAC1, GNA13, GNA12, FLNB, TSHR, GNAQ, PIK3R1, LHCGR, JAK2, JAK1, GNAI3, GNAI2, GNAS, GNA11, GNAO1, GNAI1, HSPA5, FN1, CANX, CALR, STAT3, CALCR,
    Protein Size: 253

    分子量

    28 kDa

    基因ID

    7253

    NCBI登录号

    NM_001018036, NP_001018046

    UniProt

    Q96GT6

    途径

    Thyroid Hormone Synthesis
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