CYP2C19 抗体 (Middle Region)
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北京 101111
Quick Overview for CYP2C19 抗体 (Middle Region) (ABIN2777003)
抗原
See all CYP2C19 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- QEEIERVIGR NRSPCMQDRG HMPYTDAVVH EVQRYIDLIP TSLPHAVTCD
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预测反应
- Cow: 86%, Dog: 86%, Goat: 75%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 92%, Rabbit: 93%, Rat: 92%, Sheep: 86%
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产品特性
- This is a rabbit polyclonal antibody against CYP2C19. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human CYP2C19
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anti-Cytochrome P450, Family 2, Subfamily C, Polypeptide 19 (CYP2C19) (AA 245-353) antibody
CYP2C19 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome P450, Family 2, Subfamily C, Polypeptide 19 (CYP2C19) (AA 82-108), (N-Term) antibodyCYP2C19 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB16999 unconjugated
anti-Cytochrome P450, Family 2, Subfamily C, Polypeptide 19 (CYP2C19) (C-Term) antibodyCYP2C19 适用: 人 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome P450, Family 2, Subfamily C, Polypeptide 19 (CYP2C19) (Center) antibodyCYP2C19 适用: 人, 猴 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome P450, Family 2, Subfamily C, Polypeptide 19 (CYP2C19) (AA 257-285) antibodyCYP2C19 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB17002 unconjugated
anti-Cytochrome P450, Family 2, Subfamily C, Polypeptide 19 (CYP2C19) (AA 324-373) antibodyCYP2C19 适用: 人, Cow, 绵羊 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 490 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Breast cancer risk reduction and membrane-bound catechol O-methyltransferase genetic polymorphisms." in: Cancer research, Vol. 68, Issue 14, pp. 5997-6005, (2008) (PubMed).
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: "Breast cancer risk reduction and membrane-bound catechol O-methyltransferase genetic polymorphisms." in: Cancer research, Vol. 68, Issue 14, pp. 5997-6005, (2008) (PubMed).
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- CYP2C19 (Cytochrome P450, Family 2, Subfamily C, Polypeptide 19 (CYP2C19))
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别名
- CYP2C19
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背景
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CYP2C19 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is known to metabolize many xenobiotics, including the anticonvulsive drug mephenytoin, omeprazole, diazepam and some barbiturates. Polymorphism within this gene is associated with variable ability to metabolize mephenytoin, known as the poor metabolizer and extensive metabolizer phenotypes.This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is known to metabolize many xenobiotics, including the anticonvulsive drug mephenytoin, omeprazole, diazepam and some barbiturates. Polymorphism within this gene is associated with variable ability to metabolize mephenytoin, known as the poor metabolizer and extensive metabolizer phenotypes. The gene is located within a cluster of cytochrome P450 genes on chromosome 10q24. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CPCJ, CYP 2C, CYP2C, P450C2C, P450IIC19
Protein Interaction Partner: POR,
Protein Size: 490 -
分子量
- 56 kDa
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基因ID
- 1557
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NCBI登录号
- NM_000769, NP_000760
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UniProt
- P33261
抗原
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