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CRH 抗体 (C-Term)

This anti-CRH antibody is a 兔 多克隆 antibody detecting CRH in WB. Suitable for 人, 大鼠, 小鼠, 犬, Pig, 绵羊, Cow, 兔, 豚鼠 和 斑马鱼.
产品编号 ABIN2776995
发货至: 中国

Quick Overview for CRH 抗体 (C-Term) (ABIN2776995)

抗原

See all CRH 抗体
CRH (Corticotropin Releasing Hormone (CRH))

适用

  • 85
  • 44
  • 42
  • 5
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  • 1
  • 1
  • 1
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  • 1
  • 1
人, 大鼠, 小鼠, 犬, Pig, 绵羊, Cow, 兔, 豚鼠, 斑马鱼

宿主

  • 74
  • 22
  • 2
  • 2

克隆类型

  • 80
  • 20
多克隆

标记

  • 46
  • 13
  • 11
  • 4
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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  • 1
This CRH antibody is un-conjugated

应用范围

  • 71
  • 35
  • 26
  • 15
  • 14
  • 13
  • 13
  • 9
  • 8
  • 6
  • 4
  • 3
  • 2
  • 2
Western Blotting (WB)
  • 抗原表位

    • 15
    • 8
    • 7
    • 6
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    序列

    GGHQEAPERE RRSEEPPISL DLTFHLLREV LEMARAEQLA QQAHSNRKLM

    预测反应

    Cow: 85%, Dog: 100%, Guinea Pig: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 92%, Zebrafish: 93%

    产品特性

    This is a rabbit polyclonal antibody against CRH. It was validated on Western Blot.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the C-terminal region of Human CRH
  • 限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeat freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    CRH (Corticotropin Releasing Hormone (CRH))

    别名

    CRH

    背景

    Corticotropin-releasing hormone is secreted by the paraventricular nucleus (PVN) of the hypothalamus in response to stress. Marked reduction in this protein has been observed in association with Alzheimer disease and autosomal recessive hypothalamic corticotropin deficiency has multiple and potentially fatal metabolic consequences including hypoglycemia and hepatitis. In addition to production in the hypothalamus, this protein is also synthesized in peripheral tissues, such as T lymphocytes and is highly expressed in the placenta. In the placenta it is a marker that determines the length of gestation and the timing of parturition and delivery. A rapid increase in circulating levels of the hormone occurs at the onset of parturition, suggesting that, in addition to its metabolic functions, this protein may act as a trigger for parturition.
    Alias Symbols: CRF
    Protein Interaction Partner: KRT31, CRHR1, CRH, CRHR2,
    Protein Size: 196

    分子量

    21 kDa

    基因ID

    1392

    NCBI登录号

    NM_000756, NP_000747

    UniProt

    P06850

    途径

    Positive Regulation of Peptide Hormone Secretion, Hormone Activity, Negative Regulation of Hormone Secretion, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Feeding Behaviour
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