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FGA 抗体 (Middle Region)

There are 2+ publications for this product available. The 兔多克隆 anti-FGA antibody is suitable to detect FGA in samples from 人. It has been validated for WB.

Host: Rabbit Target Name: FGA Sample Tissue: Human NCI-H226 Antibody Dilution: 1. (FGA 抗体 (Middle Region))

2 images

(2 references)

产品编号 ABIN2776978

发货至: 中国

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Quick Overview for FGA 抗体 (Middle Region) (ABIN2776978)

抗原

See all FGA 抗体

FGA (Fibrinogen alpha Chain (FGA))

适用

人

宿主

兔

克隆类型

多克隆

标记

This FGA antibody is un-conjugated

应用范围

Western Blotting (WB)

Discover our top product FGA Primary Antibody

抗原表位
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9

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1

1

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1
Middle Region

序列

SSSYSKQFTS STSYNRGDST FESKSYKMAD EAGSEADHEG THSTKRGHAK

预测反应

Human: 100%

产品特性

This is a rabbit polyclonal antibody against FGA. It was validated on Western Blot using a cell lysate as a positive control.

纯化方法

Affinity Purified

免疫原

The immunogen is a synthetic peptide directed towards the middle region of human FGA
anti-Fibrinogen alpha Chain (FGA) (AA 124-214) antibody
FGA 适用: 人 WB, ICC, ELISA, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Fibrinogen alpha Chain (FGA) (AA 39-615) antibody
FGA 适用: Cow WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Fibrinogen alpha Chain (FGA) (AA 1-218) antibody
FGA 适用: 人 WB, IP, ELISA, PLA 宿主: 小鼠 Monoclonal 1D12 unconjugated

anti-Fibrinogen alpha Chain (FGA) (AA 34-255) antibody
FGA 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Fibrinogen alpha Chain (FGA) (AA 1-218) antibody
FGA 适用: 人 WB, IHC (p), PLA 宿主: 兔 Polyclonal unconjugated

anti-Fibrinogen alpha Chain (FGA) antibody
FGA 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated

anti-Fibrinogen alpha Chain (FGA) (AA 61-160) antibody
FGA 适用: 大鼠, 小鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Fibrinogen alpha Chain (FGA) antibody
FGA 适用: 人 WB, ICC, FACS 宿主: 兔 Monoclonal 23GB5400 unconjugated Recombinant Antibody

anti-Fibrinogen alpha Chain (FGA) (AA 116-144), (N-Term) antibody
FGA 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB18707 unconjugated

anti-Fibrinogen alpha Chain (FGA) (AA 139-784) antibody
FGA 适用: 人 WB, ELISA, FACS 宿主: 兔 Polyclonal unconjugated

应用备注

Optimal working dilutions should be determined experimentally by the investigator.

说明

Antigen size: 644 AA

限制

仅限研究用
状态

Liquid

浓度

Lot specific

缓冲液

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freeze-thaw cycles.

储存条件

-20 °C

储存方法

For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Matsumoto, Matsuura, Aoki, Maehashi, Iwamoto, Ohkawa, Yoshida, Yanaga, Takada: "An efficient system for secretory production of fibrinogen using a hepatocellular carcinoma cell line." in: Hepatology research : the official journal of the Japan Society of Hepatology, Vol. 45, Issue 3, pp. 315-25, (2016) (PubMed).

Prieto-García, Zheng, Adachi, Xing, Lane, Chung, Anderson, Hansbro, Castells, Stevens: "Mast cell restricted mouse and human tryptase·heparin complexes hinder thrombin-induced coagulation of plasma and the generation of fibrin by proteolytically destroying fibrinogen." in: The Journal of biological chemistry, Vol. 287, Issue 11, pp. 7834-44, (2012) (PubMed).
抗原

FGA (Fibrinogen alpha Chain (FGA))

别名

FGA

背景

FGA is the alpha component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in its gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia, afibrinogenemia and renal amyloidosis. The protein encoded by this gene is the alpha component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia, afibrinogenemia and renal amyloidosis. Alternative splicing results in two isoforms which vary in the carboxy-terminus.
Alias Symbols: Fib2, MGC119422, MGC119423, MGC119425
Protein Interaction Partner: ASB7, ASB6, FN1, APOA1, ALB, UBC, SUMO2, MIS12, KHDRBS2, ITGA2B, SERPINA5, CDH5, SERPINF2, THBS1, F2, ITGB3, PLAT, HRG, PRRC2A, FGG, FGB, FGA, F13A1, NID1,
Protein Size: 644

分子量

66 kDa

基因ID

2243

NCBI登录号

NM_021871, NP_068657

UniProt

Q4QQH7