Coagulation Factor X 抗体 (C-Term)
Quick Overview for Coagulation Factor X 抗体 (C-Term) (ABIN2776973)
抗原
See all Coagulation Factor X (F10) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- STLMTQKTGI VSGFGRTHEK GRQSTRLKML EVPYVDRNSC KLSSSFIITQ
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预测反应
- Cow: 92%, Dog: 86%, Guinea Pig: 100%, Horse: 92%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against F10. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human F10
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anti-Coagulation Factor X (F10) (AA 21-481) antibody
F10 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor X (F10) antibodyF10 适用: 人 ELISA, IHC, IHC (p), IEP, ID 宿主: 绵羊 Polyclonal unconjugated
anti-Coagulation Factor X (F10) (AA 41-300) antibodyF10 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor X (F10) antibodyF10 适用: 人 WB, ICC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor X (F10) (C-Term) antibodyF10 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor X (F10) (AA 235-488) antibodyF10 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor X (F10) (AA 351-381), (C-Term) antibodyF10 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB19293 unconjugated
anti-Coagulation Factor X (F10) (AA 21-482) antibodyF10 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor X (F10) antibodyF10 适用: 人, 小鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor X (F10) (AA 351-400) antibodyF10 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, Pig, 猴 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 488 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Coagulation Factor X (F10)
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别名
- F10
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背景
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F10 is the vitamin K-dependent coagulation factor X of the blood coagulation cascade. This factor undergoes multiple processing steps before its preproprotein is converted to a mature two-chain form by the excision of the tripeptide RKR. Two chains of the factor are held together by 1 or more disulfide bonds, the light chain contains 2 EGF-like domains, while the heavy chain contains the catalytic domain which is structurally homologous to those of the other hemostatic serine proteases. The mature factor is activated by the cleavage of the activation peptide by factor IXa (in the intrisic pathway), or by factor VIIa (in the extrinsic pathway). The activated factor then converts prothrombin to thrombin in the presence of factor Va, Ca+2, and phospholipid during blood clotting.This gene encodes the vitamin K-dependent coagulation factor X of the blood coagulation cascade. This factor undergoes multiple processing steps before its preproprotein is converted to a mature two-chain form by the excision of the tripeptide RKR. Two chains of the factor are held together by 1 or more disulfide bonds, the light chain contains 2 EGF-like domains, while the heavy chain contains the catalytic domain which is structurally homologous to those of the other hemostatic serine proteases. The mature factor is activated by the cleavage of the activation peptide by factor IXa (in the intrisic pathway), or by factor VIIa (in the extrinsic pathway). The activated factor then converts prothrombin to thrombin in the presence of factor Va, Ca+2, and phospholipid during blood clotting. Mutations of this gene result in factor X deficiency, a hemorrhagic condition of variable severity. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: FX, FXA
Protein Interaction Partner: UBC, GAD2, SERPINA10, HIST1H1C, MGST3, PRKAB1, SERPINA5, SERPINB8, F8, F10, F7, F5, PROS1, PLAT, PLG, SERPINB6, TFPI, APOH, GGCX, F3,
Protein Size: 488 -
分子量
- 29 kDa
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基因ID
- 2159
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NCBI登录号
- NM_000504, NP_000495
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UniProt
- P00742
抗原
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