TSH receptor 抗体 (N-Term)
Quick Overview for TSH receptor 抗体 (N-Term) (ABIN2776955)
抗原
See all TSH receptor (TSHR) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- ELIARNTWTL KKLPLSLSFL HLTRADLSYP SHCCAFKNQK KIRGILESLM
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%
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产品特性
- This is a rabbit polyclonal antibody against TSHR. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human TSHR
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 764 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- TSH receptor (TSHR) (Thyroid Stimulating Hormone Receptor (TSHR))
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别名
- TSHR
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背景
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TSHR is receptor for thyrothropin. It plays a central role in controlling thyroid cell metabolism. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. It also acts as a receptor for thyrostimulin (GPA2+GPB5).
Alias Symbols: LGR3, MGC75129, hTSHR-I, CHNG1
Protein Interaction Partner: ADRB2, SCRIB, UBC, TSHB, RABAC1, GNA13, GNA12, FLNB, TSHR, GNAQ, PIK3R1, LHCGR, JAK2, JAK1, GNAI3, GNAI2, GNAS, GNA11, GNAO1, GNAI1, HSPA5, FN1, CANX, CALR, STAT3, CALCR,
Protein Size: 764 -
分子量
- 84 kDa
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基因ID
- 7253
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NCBI登录号
- NM_000369, NP_000360
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UniProt
- P16473
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途径
- Thyroid Hormone Synthesis
抗原
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