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FECH 抗体 (N-Term)

FECH 适用: 人, 小鼠, 大鼠, 犬, 兔, Cow, 豚鼠, 马, 斑马鱼, Saccharomyces cerevisiae WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2776936
发货至: 中国
  • 抗原 See all FECH 抗体
    FECH (Ferrochelatase (FECH))
    抗原表位
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 32
    • 21
    • 21
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, 犬, 兔, Cow, 豚鼠, 马, 斑马鱼, Saccharomyces cerevisiae
    宿主
    • 28
    • 4
    克隆类型
    • 30
    • 2
    多克隆
    标记
    • 18
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FECH antibody is un-conjugated
    应用范围
    • 31
    • 13
    • 9
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB)
    序列
    LDRDLMTLPI QNKLAPFIAK RRTPKIQEQY RRIGGGSPIK IWTSKQGEGM
    预测反应
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 77%, Zebrafish: 86%
    产品特性
    This is a rabbit polyclonal antibody against FECH. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Protein A purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human FECH
    Top Product
    Discover our top product FECH Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 429 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Miyake, Ishii, Kawashima, Kodama, Sugano, Fujimoto, Hirao: "siRNA-mediated knockdown of the heme synthesis and degradation pathways: modulation of treatment effect of 5-aminolevulinic acid-based photodynamic therapy in urothelial cancer cell lines." in: Photochemistry and photobiology, Vol. 85, Issue 4, pp. 1020-7, (2009) (PubMed).

  • 抗原
    FECH (Ferrochelatase (FECH))
    别名
    FECH (FECH 产品)
    别名
    AI894116 antibody, Fcl antibody, fch antibody, zgc:109851 antibody, EPP antibody, FCE antibody, CG2098 antibody, Dmel\\CG2098 antibody, GB15952 antibody, ferrochelatase L homeolog antibody, ferrochelatase antibody, Ferrochelatase antibody, ferrochelatase, mitochondrial antibody, ferrochelatase HemH antibody, ferrochelatase (predicted) antibody, fech.L antibody, hemH antibody, Fech antibody, FECH antibody, fech antibody, FeCH antibody, LOC409922 antibody, hem15 antibody, APH_RS01140 antibody
    背景
    Ferrochelatase is localized to the mitochondrion where it catalyzes the insertion of the ferrous form of iron into protoporphyrin IX in the heme synthesis pathway. Defects in ferrochelatase are associated with protoporphyria.Ferrochelatase is localized to the mitochondrion where it catalyzes the insertion of the ferrous form of iron into protoporphyrin IX in the heme synthesis pathway. Defects in ferrochelatase are associated with protoporphyria. Two transcript variants encoding different isoforms have been found for this gene.
    Alias Symbols: EPP, FCE
    Protein Interaction Partner: PPP2R1A, UBC, NEDD8, MDM2, FBXO6, gag-pol, COPS5, COPS6, CUL3, ELAVL1, MINOS1, MME, USP42, USP20, ABCB7, FECH,
    Protein Size: 429
    分子量
    47 kDa
    基因ID
    2235
    NCBI登录号
    NM_001012515, NP_001012533
    UniProt
    Q8NAN0
    途径
    Transition Metal Ion Homeostasis
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