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Complement C2 抗体 (N-Term)

This 兔 多克隆 antibody specifically detects Complement C2 in WB. It exhibits reactivity toward 人, 大鼠, 小鼠, 犬, 马, Pig, Cow, 兔 和 豚鼠.
产品编号 ABIN2776929
发货至: 中国
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Quick Overview for Complement C2 抗体 (N-Term) (ABIN2776929)

抗原

See all Complement C2 抗体
Complement C2

适用

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人, 大鼠, 小鼠, 犬, 马, Pig, Cow, 兔, 豚鼠

宿主

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兔

克隆类型

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多克隆

标记

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This Complement C2 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    N-Term

    原理

    C2 Antibody - N-terminal region

    序列

    EPICRQPYSY DFPEDVAPAL GTSFSHMLGA TNPTQKTKES LGRKIQIQRS

    预测反应

    Cow: 100%, Dog: 93%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

    产品特性

    This is a rabbit polyclonal antibody against C2. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human C2
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP41668-100UG

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5 mg/mL

    缓冲液

    Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    prevent freeze-thaw cycles

    储存条件

    4 °C,-20 °C

    储存方法

    For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    Complement C2

    别名

    C2

    背景

    Background Information: Component C2 is a serum glycoprotein that functions as part of the classical pathway of the complement system. Activated C1 cleaves C2 into C2a and C2b. The serine proteinase C2a then combines with complement factor 4b to create the C3 or C5 convertase. Deficiency of C2 has been reported to associated with certain autoimmune diseases and SNPs in this gene have been associated with altered susceptibility to age-related macular degeneration. This gene localizes within the class III region of the MHC on the short arm of chromosome 6. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described in publications but their full-length sequence has not been determined.

    Gene Name: complement C2

    Alternative Symbols: CO2, ARMD14

    Protein Name: complement C2

    分子量

    81kDa

    基因ID

    717

    NCBI登录号

    NP_000054

    UniProt

    P06681
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