ALAS2 抗体 (N-Term)
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北京 101111
Quick Overview for ALAS2 抗体 (N-Term) (ABIN2776923)
抗原
See all ALAS2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- ALAS2 Antibody - N-terminal region
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序列
- CPILATQGPN CSQIHLKATK AGGDSPSWAK GHCPFMLSEL QDGKSKIVQK
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预测反应
- Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 79%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against ALAS2. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human ALAS2
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP41658-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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: "Non-genomic immunosuppressive actions of progesterone inhibits PHA-induced alkalinization and activation in T cells." in: Journal of cellular biochemistry, Vol. 99, Issue 1, pp. 292-304, (2006) (PubMed).
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- ALAS2 (Aminolevulinate, delta-, Synthase 2 (ALAS2))
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别名
- ALAS2
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背景
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Background Information: ALAS2 specifies an erythroid-specific mitochondrially located enzyme. The protein catalyzes the first step in the heme biosynthetic pathway. Defects in its gene cause X-linked pyridoxine-responsive sideroblastic anemia. Alternatively spliced transcript variants encoding different isoforms have been identified.The product of this gene specifies an erythroid-specific mitochondrially located enzyme. The encoded protein catalyzes the first step in the heme biosynthetic pathway. Defects in this gene cause X-linked pyridoxine-responsive sideroblastic anemia. Alternatively spliced transcript variants encoding different isoforms have been identified.
Gene Name: Aminolevulinate, delta-, synthase 2
Alternative Symbols: ASB, ANH1, XLSA, ALASE, XLDPP, XLEPP, ALAS-E, SIDBA1
Protein Name: 5-aminolevulinate synthase, erythroid-specific, mitochondrial
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分子量
- 60kDa
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基因ID
- 212
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NCBI登录号
- NP_001033056
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UniProt
- P22557
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途径
- Transition Metal Ion Homeostasis
抗原
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