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PDZK1 抗体 (N-Term)

PDZK1 适用: 人, 小鼠, 大鼠, 马, 犬, 豚鼠, 兔, Cow WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2776855
发货至: 中国
  • 抗原 See all PDZK1 抗体
    PDZK1 (PDZ Domain Containing 1 (PDZK1))
    抗原表位
    • 12
    • 8
    • 7
    • 7
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    人, 小鼠, 大鼠, 马, 犬, 豚鼠, 兔, Cow
    宿主
    • 44
    • 7
    • 1
    • 1
    克隆类型
    • 46
    • 7
    多克隆
    标记
    • 25
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PDZK1 antibody is un-conjugated
    应用范围
    • 49
    • 25
    • 18
    • 13
    • 9
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    序列
    NSVTLLVLDG DSYEKAVKTR VDLKELGQSQ KEQGLSDNIL SPVMNGGVQT
    预测反应
    Cow: 92%, Dog: 92%, Guinea Pig: 100%, Horse: 92%, Human: 100%, Mouse: 100%, Rabbit: 92%, Rat: 100%
    产品特性
    This is a rabbit polyclonal antibody against PDZK1. It was validated on Western Blot.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human PDZK1
    Top Product
    Discover our top product PDZK1 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 519 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    PDZK1 (PDZ Domain Containing 1 (PDZK1))
    别名
    PDZK1 (PDZK1 产品)
    别名
    xpdzk1 antibody, PDZK1 antibody, CAP70 antibody, CLAMP antibody, NHERF-3 antibody, NHERF3 antibody, PDZD1 antibody, 1700023D20Rik antibody, 2610507N21Rik antibody, 4921513F16Rik antibody, AI267131 antibody, AI314638 antibody, AL022680 antibody, D3Ertd537e antibody, Pdzd1 antibody, mPDZK1 antibody, Clamp antibody, PDZ domain containing 1 antibody, PDZ domain containing 1 L homeolog antibody, PDZK1 antibody, pdzk1.L antibody, pdzk1 antibody, Pdzk1 antibody
    背景
    PDZK1 is a scaffold protein that connects plasma membrane proteins and regulatory components, regulating their surface expression in epithelial cells apical domains. It may be involved in the coordination of a diverse range of regulatory processes for ion transport and second messenger cascades. In complex with SLC9A3R1, it may cluster proteins that are functionally dependent in a mutual fashion and modulate the trafficking and the activity of the associated membrane proteins. PDZK1 may play a role in the cellular mechanisms associated with multidrug resistance through its interaction with ABCC2 and PDZK1IP1. PDZK1 may potentiate the CFTR chloride channel activity. It may function to connect SCARB1 with the cellular machineries for intracellular cholesterol transport and/or metabolism. PDZK1 may be involved in the regulation of proximal tubular Na+-dependent inorganic phosphate cotransport therefore playing an important role in tubule function.
    Alias Symbols: CAP70, CLAMP, NHERF3, PDZD1, NHERF-3
    Protein Interaction Partner: AKT1, CDC37, Ptgir, ABCC4, CFTR, APP, Klhl17, Syngap1, Dlg4, SLC26A6, SLC22A4, SLCO1A2, SLC15A2, PDZK1IP1, SLC22A11, SLC22A12, AKAP10, SLC22A5, ABCC2, SCARB1, CLCN3, PEX5, ABCA1, SSTR5, SLC17A1, SLC9A3, GFAP, SLC34A3, FARP2, SLK, SLC9A3R1, SLC9A3R2, UBE2I
    Protein Size: 519
    分子量
    57 kDa
    基因ID
    5174
    NCBI登录号
    NM_002614, NP_002605
    UniProt
    Q5T2W1
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