PDZK1 抗体 (N-Term)
Quick Overview for PDZK1 抗体 (N-Term) (ABIN2776855)
抗原
See all PDZK1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- NSVTLLVLDG DSYEKAVKTR VDLKELGQSQ KEQGLSDNIL SPVMNGGVQT
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预测反应
- Cow: 92%, Dog: 92%, Guinea Pig: 100%, Horse: 92%, Human: 100%, Mouse: 100%, Rabbit: 92%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against PDZK1. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human PDZK1
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anti-PDZ Domain Containing 1 (PDZK1) (AA 1-519) antibody
PDZK1 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1C3-2B11 unconjugated
anti-PDZ Domain Containing 1 (PDZK1) (AA 1-520) antibodyPDZK1 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 小鼠 Monoclonal 1C3-2B11 unconjugated
anti-PDZ Domain Containing 1 (PDZK1) (AA 1-519) antibodyPDZK1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1E9 unconjugated
anti-PDZ Domain Containing 1 (PDZK1) (C-Term) antibodyPDZK1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-PDZ Domain Containing 1 (PDZK1) (AA 1-519) antibodyPDZK1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-PDZ Domain Containing 1 (PDZK1) (N-Term) antibodyPDZK1 适用: 人, 小鼠, 犬, 马, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-PDZ Domain Containing 1 (PDZK1) (AA 80-129) antibodyPDZK1 适用: 人, 小鼠, 大鼠, 豚鼠, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-PDZ Domain Containing 1 (PDZK1) (AA 1-260) antibodyPDZK1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-PDZ Domain Containing 1 (PDZK1) (N-Term) antibodyPDZK1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-PDZ Domain Containing 1 (PDZK1) (AA 196-224) antibodyPDZK1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 519 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- PDZK1 (PDZ Domain Containing 1 (PDZK1))
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别名
- PDZK1
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背景
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PDZK1 is a scaffold protein that connects plasma membrane proteins and regulatory components, regulating their surface expression in epithelial cells apical domains. It may be involved in the coordination of a diverse range of regulatory processes for ion transport and second messenger cascades. In complex with SLC9A3R1, it may cluster proteins that are functionally dependent in a mutual fashion and modulate the trafficking and the activity of the associated membrane proteins. PDZK1 may play a role in the cellular mechanisms associated with multidrug resistance through its interaction with ABCC2 and PDZK1IP1. PDZK1 may potentiate the CFTR chloride channel activity. It may function to connect SCARB1 with the cellular machineries for intracellular cholesterol transport and/or metabolism. PDZK1 may be involved in the regulation of proximal tubular Na+-dependent inorganic phosphate cotransport therefore playing an important role in tubule function.
Alias Symbols: CAP70, CLAMP, NHERF3, PDZD1, NHERF-3
Protein Interaction Partner: AKT1, CDC37, Ptgir, ABCC4, CFTR, APP, Klhl17, Syngap1, Dlg4, SLC26A6, SLC22A4, SLCO1A2, SLC15A2, PDZK1IP1, SLC22A11, SLC22A12, AKAP10, SLC22A5, ABCC2, SCARB1, CLCN3, PEX5, ABCA1, SSTR5, SLC17A1, SLC9A3, GFAP, SLC34A3, FARP2, SLK, SLC9A3R1, SLC9A3R2, UBE2I
Protein Size: 519 -
分子量
- 57 kDa
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基因ID
- 5174
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NCBI登录号
- NM_002614, NP_002605
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UniProt
- Q5T2W1
抗原
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