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MAT1A 抗体 (C-Term)

This anti-MAT1A antibody is a 兔 多克隆 antibody detecting MAT1A in WB. Suitable for 人, 小鼠, 大鼠, 犬, Cow, 兔, 豚鼠, 马 和 斑马鱼. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN2776786
发货至: 中国

Quick Overview for MAT1A 抗体 (C-Term) (ABIN2776786)

抗原

See all MAT1A 抗体
MAT1A (Methionine Adenosyltransferase I, alpha (MAT1A))

适用

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人, 小鼠, 大鼠, 犬, Cow, 兔, 豚鼠, 马, 斑马鱼

宿主

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  • 2

克隆类型

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多克隆

标记

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This MAT1A antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    C-Term

    序列

    VAKSLVKAGL CRRVLVQVSY AIGVAEPLSI SIFTYGTSQK TERELLDVVH

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 86%, Rat: 93%, Zebrafish: 79%

    产品特性

    This is a rabbit polyclonal antibody against MAT1A. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Protein A purified

    免疫原

    The immunogen is a synthetic peptide directed towards the C terminal region of human MAT1A
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 395 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Hu, Lausted, Yoo, Yan, Brightman, Chen, Wang, Bu, Hood: "Quantitative liver-specific protein fingerprint in blood: a signature for hepatotoxicity." in: Theranostics, Vol. 4, Issue 2, pp. 215-28, (2014) (PubMed).

  • 抗原

    MAT1A (Methionine Adenosyltransferase I, alpha (MAT1A))

    别名

    MAT1A

    背景

    MAT1A catalyzes a two-step reaction that involves the transfer of the adenosyl moiety of ATP to methionine to form S-adenosylmethionine and tripolyphosphate, which is subsequently cleaved to PPi and Pi. S-adenosylmethionine is the source of methyl groups for most biological methylations. MAT1A is found as a homotetramer (MAT I) or a homodimer (MAT III) whereas a third form, MAT II (gamma), is encoded by the MAT2A gene. Mutations in its gene are associated with methionine adenosyltransferase deficiency.This gne encodes methionine adenosyltransferase I (alpha isoform), which catalyzes the formation of S-adenosylmethionine from methionine and ATP. Methionine adenosyltransferase deficiency is caused by recessive and dominant mutations, the latter identified in autosomal dominant persistant hypermethioninemia.
    Alias Symbols: MAT, MATA1, SAMS, SAMS1
    Protein Interaction Partner: MAT1A, UBC, IST1, MVK, MAT2A,
    Protein Size: 395

    分子量

    44 kDa

    基因ID

    4143

    NCBI登录号

    NM_000429, NP_000420

    UniProt

    Q00266

    途径

    Mitotic G1-G1/S Phases, M Phase, Ribonucleoside Biosynthetic Process, Methionine Biosynthetic Process
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