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TNNI3 抗体 (Middle Region)

This anti-TNNI3 antibody is a 兔 多克隆 antibody detecting TNNI3 in WB 和 IHC. Suitable for 人, 小鼠, 大鼠, 犬, Cow, 兔, 山羊, 豚鼠, 马 和 斑马鱼.
产品编号 ABIN2776782
发货至: 中国

Quick Overview for TNNI3 抗体 (Middle Region) (ABIN2776782)

抗原

See all TNNI3 抗体
TNNI3 (Cardiac Troponin I (TNNI3))

适用

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人, 小鼠, 大鼠, 犬, Cow, 兔, 山羊, 豚鼠, 马, 斑马鱼

宿主

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克隆类型

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多克隆

标记

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This TNNI3 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    Middle Region

    序列

    RVRISADAMM QALLGARAKE SLDLRAHLKQ VKKEDTEKEN REVGDWRKNI

    预测反应

    Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

    产品特性

    This is a rabbit polyclonal antibody against TNNI3. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the middle region of human TNNI3
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 210 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    TNNI3 (Cardiac Troponin I (TNNI3))

    别名

    TNNI3

    背景

    Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit, blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. TNNI3 is the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues.Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit, blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: CMH7, MGC116817, TNNC1, cTnI, RCM1, CMD2A, CMD1FF
    Protein Interaction Partner: TNNC2, TRIM63, TRIM55, RCAN3, TNNC1, TNNI3K, PKD2L1, TNNI3, TNNT2, TNNT1, PRKCA, PAPPA, PKD2, ACTA1, LYST,
    Protein Size: 210

    分子量

    23 kDa

    基因ID

    7137

    NCBI登录号

    NM_000363, NP_000354

    UniProt

    Q59H18
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