ELAC2 抗体 (C-Term)
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北京 101111
Quick Overview for ELAC2 抗体 (C-Term) (ABIN2776757)
抗原
See all ELAC2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- ITCNPEEFIV EALQLPNFQQ SVQEYRRSAQ DGPAPAEKRS QYPEIIFLGT
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预测反应
- Dog: 100%, Human: 100%, Mouse: 83%, Rat: 83%
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产品特性
- This is a rabbit polyclonal antibody against ELAC2. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human ELAC2
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeat freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- ELAC2 (ElaC Homolog 2 (ELAC2))
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别名
- ELAC2
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背景
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The protein encoded by this gene has a C-terminal domain with tRNA 3' processing endoribonuclease activity, which catalyzes the removal of the 3' trailer from precursor tRNAs. The protein also interacts with activated Smad family member 2 (Smad2) and its nuclear partner forkhead box H1 (also known as FAST-1), and reduced expression can suppress transforming growth factor-beta induced growth arrest. Mutations in this gene result in an increased risk of prostate cancer. Multiple transcript variants encoding different isoforms have been found for this gene.
Protein Interaction Partner: UBC, SUMO2, SUMO1, NEDD8, XPO5, SNX5, ARIH1, TNPO3, WDR4, IPO7, TSN, SARS, PPP2CB, PFDN1, NRD1, HARS, FEN1, FOXH1, SMAD3, SMAD2, COPS5, ASCC2, NDUFA7, GOLM1, CUX1, PUF60,
Protein Size: 501 -
分子量
- 55 kDa
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基因ID
- 60528
抗原
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