ADAM12 抗体 (N-Term)
Quick Overview for ADAM12 抗体 (N-Term) (ABIN2776751)
抗原
See all ADAM12 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- VELVIVADNR EFQRQGKDLE KVKQRLIEIA NHVDKFYRPL NIRIVLVGVE
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%
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产品特性
- This is a rabbit polyclonal antibody against ADAM12. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human ADAM12
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 909 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- ADAM12 (ADAM Metallopeptidase Domain 12 (ADAM12))
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别名
- ADAM12
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背景
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ADAM12 is a member of the ADAM (a disintegrin and metalloprotease) protein family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. ADAM12 gene has two alternatively spliced transcripts: a shorter secreted form and a longer membrane-bound form. The shorter form is found to stimulate myogenesis.This gene encodes a member of the ADAM (a disintegrin and metalloprotease) protein family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This gene has two alternatively spliced transcripts: a shorter secreted form and a longer membrane-bound form. The shorter form is found to stimulate myogenesis.
Alias Symbols: MCMP, MCMPMltna, MLTN, MLTNA
Protein Interaction Partner: SH3D19, PACSIN3, FSTL3, SRC, PIK3R1, YES1, IGFBP5, IGFBP3, EGF, GRB2, ACTN2,
Protein Size: 909 -
分子量
- 100 kDa
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基因ID
- 8038
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NCBI登录号
- NM_021641, NP_067673
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UniProt
- O43184
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途径
- EGFR Signaling Pathway
抗原
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