ERI1 抗体 (N-Term)
(1 reference)Quick Overview for ERI1 抗体 (N-Term) (ABIN2776656)
抗原
See all ERI1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- SKFITSSASD FSDPVYKEIA ITNGCINRMS KEELRAKLSE FKLETRGVKD
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预测反应
- Cow: 93%, Dog: 100%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Mouse: 85%, Pig: 93%, Rabbit: 100%, Rat: 79%
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产品特性
- This is a rabbit polyclonal antibody against THEX1. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human ERI1
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anti-Exoribonuclease 1 (ERI1) antibody
ERI1 适用: 人, 大鼠, 猴 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 1B3 unconjugated
anti-Exoribonuclease 1 (ERI1) (AA 2-66) antibodyERI1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Exoribonuclease 1 (ERI1) (AA 1-345) antibodyERI1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Exoribonuclease 1 (ERI1) (AA 51-150) antibodyERI1 适用: 小鼠 ELISA, IF (cc), IF (p), ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Exoribonuclease 1 (ERI1) (C-Term) antibodyERI1 适用: 人, 小鼠, 大鼠 WB, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Exoribonuclease 1 (ERI1) (AA 231-280) antibodyERI1 适用: 人, 小鼠, 大鼠, 犬, 兔, Cow, 豚鼠, 马, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Exoribonuclease 1 (ERI1) (AA 29-78) antibodyERI1 适用: 人, 犬, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-Exoribonuclease 1 (ERI1) (C-Term) antibodyERI1 适用: 人, 小鼠, 大鼠, 犬 WB 宿主: 兔 Polyclonal unconjugated
anti-Exoribonuclease 1 (ERI1) (AA 2-249) antibodyERI1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Exoribonuclease 1 (ERI1) antibodyERI1 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 349 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Genetic and biochemical characterization of Drosophila Snipper: A promiscuous member of the metazoan 3'hExo/ERI-1 family of 3' to 5' exonucleases." in: RNA (New York, N.Y.), Vol. 12, Issue 12, pp. 2103-17, (2006) (PubMed).
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: "Genetic and biochemical characterization of Drosophila Snipper: A promiscuous member of the metazoan 3'hExo/ERI-1 family of 3' to 5' exonucleases." in: RNA (New York, N.Y.), Vol. 12, Issue 12, pp. 2103-17, (2006) (PubMed).
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- ERI1 (Exoribonuclease 1 (ERI1))
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别名
- THEX1
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背景
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RNA exonuclease that binds to the 3'-end of histone mRNAs and degrades them, suggesting that it plays an essential role in histone mRNA decay after replication. A 2' and 3'-hydroxyl groups at the last nucleotide of the histone 3'-end is required for efficient degradation of RNA substrates. Also able to degrade the 3'-overhangs of short interfering RNAs (siRNAs) in vitro, suggesting a possible role as regulator of RNA interference (RNAi). Requires for binding the 5'-ACCCA-3' sequence present in stem-loop structure. Able to bind other mRNAs. Required for 5.8S rRNA 3'-end processing. Also binds to 5.8s ribosomal RNA. Binds with high affinity to the stem-loop structure of replication-dependent histone pre-mRNAs.
Alias Symbols: HEXO, THEX1, 3'HEXO
Protein Interaction Partner: UBC, HNRNPD, HHV8GK18_gp81, SLBP,
Protein Size: 38 -
分子量
- 349 kDa
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基因ID
- 90459
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NCBI登录号
- NM_153332, NP_699163
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UniProt
- Q8IV48
抗原
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