HEXIM2 抗体 (N-Term)
Quick Overview for HEXIM2 抗体 (N-Term) (ABIN2776632)
抗原
See all HEXIM2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- MATPNQTACN AESPVALEEA KTSGAPGSPQ TPPERHDSGG SLPLTPRMES
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预测反应
- Dog: 93%, Horse: 79%, Human: 100%, Pig: 86%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against HEXIM2. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human HEXIM2
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 286 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- HEXIM2 (Hexamthylene Bis-Acetamide Inducible 2 (HEXIM2))
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别名
- HEXIM2
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背景
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HEXIM2 belongs to the HEXIM family. It is transcriptional regulator which functions as a general RNA polymerase II transcription inhibitor.In cooperation with 7SK snRNA, HEXIM2 sequesters P-TEFb in a large inactive 7SK snRNP complex preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation.
Alias Symbols: FLJ32384, L3
Protein Interaction Partner: TCF12, CCDC36, HEXIM2, PRDM14, RNPS1, TADA3, SPRY2, SPRY1, PIN1, PIM1, MEOX2, GATA1, CDK9, RN7SK, HEXIM1, TERF2, TERF1, MEPCE, CCNT1,
Protein Size: 286 -
分子量
- 31 kDa
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基因ID
- 124790
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NCBI登录号
- NM_144608, NP_653209
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UniProt
- Q96MH2
抗原
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