EXOSC6 抗体 (N-Term)
Quick Overview for EXOSC6 抗体 (N-Term) (ABIN2776614)
抗原
See all EXOSC6 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- MPGDHRRIRG PEESQPPQLY AADEEEAPGT RDPTRLRPVY ARAGLLSQAK
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预测反应
- Cow: 93%, Human: 100%, Mouse: 88%, Pig: 86%, Rat: 93%
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产品特性
- This is a rabbit polyclonal antibody against EXOSC6. It was validated on Western Blot and immunohistochemistry.
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纯化方法
- Protein A purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human EXOSC6
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anti-Exosome Component 6 (EXOSC6) (N-Term) antibody
EXOSC6 适用: 人, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Exosome Component 6 (EXOSC6) (N-Term) antibodyEXOSC6 适用: 人, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Exosome Component 6 (EXOSC6) (N-Term) antibodyEXOSC6 适用: 人, 小鼠, 大鼠, Cow, 猴, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Exosome Component 6 (EXOSC6) (N-Term) antibodyEXOSC6 适用: 人, 小鼠, 大鼠, 犬 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 272 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- EXOSC6 (Exosome Component 6 (EXOSC6))
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别名
- EXOSC6
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背景
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EXOSC6 constitutes one of the subunits of the multisubunit particle called exosome, which mediates mRNA degradation. The composition of human exosome is similar to its yeast counterpart. This protein is homologous to the yeast Mtr3 protein. Its exact function is not known, however, it has been shown using a cell-free RNA decay system that the exosome is required for rapid degradation of unstable mRNAs containing AU-rich elements (AREs), but not for poly(A) shortening. The exosome does not recognize ARE-containing mRNAs on its own, but requires ARE-binding proteins that could interact with the exosome and recruit it to unstable mRNAs, thereby promoting their rapid degradation.This gene product constitutes one of the subunits of the multisubunit particle called exosome, which mediates mRNA degradation. The composition of human exosome is similar to its yeast counterpart. This protein is homologous to the yeast Mtr3 protein. Its exact function is not known, however, it has been shown using a cell-free RNA decay system that the exosome is required for rapid degradation of unstable mRNAs containing AU-rich elements (AREs), but not for poly(A) shortening. The exosome does not recognize ARE-containing mRNAs on its own, but requires ARE-binding proteins that could interact with the exosome and recruit it to unstable mRNAs, thereby promoting their rapid degradation.
Alias Symbols: p11, EAP4, MTR3, Mtr3p, hMtr3p
Protein Interaction Partner: CEP250, DCP1B, EXOSC6, CHPF, MIF4GD, XRN1, NDUFA13, MRPL4, EXOSC1, MRPS18B, UPF2, RAB3GAP2, SKIV2L2, GSE1, EXOSC7, EXOSC8, ZFP36, TUFM, EXOSC10, MAN2C1, ESRRA, C1QBP, AICDA, DIS3L, EXOSC4, EXOSC3, CUL3, ELAVL1, HDGF, UBC, EXOSC5, DNAJC30, MOCS3, MPP6, EXO
Protein Size: 272 -
分子量
- 30 kDa
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基因ID
- 118460
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NCBI登录号
- NM_058219, NP_478126
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UniProt
- Q5RKV6
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途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
抗原
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