NXF5 抗体 (Middle Region)
Quick Overview for NXF5 抗体 (Middle Region) (ABIN2776599)
抗原
See all NXF5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- ITERNFPELL SLNLCNNKLY QLDGLSDITE KAPKVKTLNL SKNKLESAWE
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预测反应
- Dog: 86%, Human: 100%, Mouse: 79%, Rabbit: 86%, Rat: 86%
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产品特性
- This is a rabbit polyclonal antibody against NXF5. It was validated on Western Blot and immunohistochemistry.
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纯化方法
- Protein A purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human NXF5
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 397 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- NXF5 (Nuclear RNA Export Factor 5 (NXF5))
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别名
- NXF5
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背景
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NXF5 is one member of a family of nuclear RNA export factors. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2)-like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. The LRRs and NTF2-like domains are required for export activity.This gene is one member of a family of nuclear RNA export factor genes. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2)-like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. The LRRs and NTF2-like domains are required for export activity. Alternative splicing seems to be a common mechanism in this gene family. Five transcript variants that encode different isoforms have been found for this gene.
Protein Interaction Partner: NXF1,
Protein Size: 397 -
分子量
- 44 kDa
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基因ID
- 55998
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NCBI登录号
- NM_032946, NP_116564
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UniProt
- Q9H1B4
抗原
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