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HNRNPC 抗体 (N-Term)

This anti-HNRNPC antibody is a 兔 多克隆 antibody detecting HNRNPC in WB. Suitable for 人, 大鼠, 小鼠, 兔, 犬 和 Pig. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN2776586
发货至: 中国

Quick Overview for HNRNPC 抗体 (N-Term) (ABIN2776586)

抗原

See all HNRNPC 抗体
HNRNPC (Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) (HNRNPC))

适用

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人, 大鼠, 小鼠, 兔, 犬, Pig

宿主

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克隆类型

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多克隆

标记

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This HNRNPC antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    N-Term

    序列

    LDINLAAEPK VNRGKAGVKR SAAEMYGSVT EHPSPSPLLS SSFDLDYDFQ

    预测反应

    Dog: 93%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 93%, Rat: 93%

    产品特性

    This is a rabbit polyclonal antibody against HNRPC. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human HNRPC
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 303 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Hayakawa, Fujikane, Ito, Matsumoto, Nakayama, Sekiguchi: "Human proteins that specifically bind to 8-oxoguanine-containing RNA and their responses to oxidative stress." in: Biochemical and biophysical research communications, Vol. 403, Issue 2, pp. 220-4, (2010) (PubMed).

  • 抗原

    HNRNPC (Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) (HNRNPC))

    别名

    HNRPC

    背景

    HNRPC belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein can act as a tetramer and is involved in the assembly of 40S hnRNP particles.This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has one RRM domain that binds to RNAs. Two alternatively spliced transcript variants have been described for this gene.
    Alias Symbols: C1, C2, HNRNP, MGC104306, MGC105117, MGC117353, MGC131677, SNRPC, hnRNPC, HNRPC
    Protein Interaction Partner: SUMO1P1, RALYL, RBM41, ZFYVE26, SUMO1, UBE2I, UBC, SDCBP, LMO2, KPNA4, KPNA3, KPNA2, HNRNPC, EPS8, BRIP1, PALB2, BRCA2, BRCA1, BARD1, CEP250, SUMO2, SUMO3, RAD51, IVNS1ABP, STAU1, MDM2, ERG, EED, RNF2, rev, CDKN2A, PARK2, SRPK2, SRPK1, CLK3, TARDBP, YWHAQ
    Protein Size: 303

    分子量

    33 kDa

    基因ID

    3183

    NCBI登录号

    NM_031314, NP_112604

    UniProt

    P07910
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