DGCR8 抗体 (N-Term)
(3 references)Quick Overview for DGCR8 抗体 (N-Term) (ABIN2776557)
抗原
See all DGCR8 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- DKKDEENELD QEKRVEYAVL DELEDFTDNL ELDEEGAGGF TAKAIVQRDR
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预测反应
- Cow: 85%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 77%
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产品特性
- This is a rabbit polyclonal antibody against DGCR8. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human DGCR8
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anti-DiGeorge Syndrome Critical Region Gene 8 (DGCR8) (AA 1-773) antibody
DGCR8 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-DiGeorge Syndrome Critical Region Gene 8 (DGCR8) (AA 1-773) antibodyDGCR8 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-DiGeorge Syndrome Critical Region Gene 8 (DGCR8) (AA 675-771) antibodyDGCR8 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 4G3 unconjugated
anti-DiGeorge Syndrome Critical Region Gene 8 (DGCR8) (C-Term) antibodyDGCR8 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-DiGeorge Syndrome Critical Region Gene 8 (DGCR8) (AA 675-771) antibodyDGCR8 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-DiGeorge Syndrome Critical Region Gene 8 (DGCR8) (AA 180-229) antibodyDGCR8 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 猴, Pig WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-DiGeorge Syndrome Critical Region Gene 8 (DGCR8) (AA 1-773) antibodyDGCR8 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-DiGeorge Syndrome Critical Region Gene 8 (DGCR8) (AA 439-466) antibodyDGCR8 适用: 人 WB, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-DiGeorge Syndrome Critical Region Gene 8 (DGCR8) antibodyDGCR8 适用: 人 WB, ELISA 宿主: 兔 Monoclonal 2H2 unconjugated Recombinant Antibody
anti-DiGeorge Syndrome Critical Region Gene 8 (DGCR8) (pSer377) antibodyDGCR8 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 773 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "DGCR8 is essential for tumor progression following PTEN loss in the prostate." in: EMBO reports, Vol. 16, Issue 9, pp. 1219-32, (2015) (PubMed).
: "Localization and sub-cellular shuttling of HTLV-1 tax with the miRNA machinery." in: PLoS ONE, Vol. 7, Issue 7, pp. e40662, (2012) (PubMed).
: "NMDA mediated contextual conditioning changes miRNA expression." in: PLoS ONE, Vol. 6, Issue 9, pp. e24682, (2011) (PubMed).
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: "DGCR8 is essential for tumor progression following PTEN loss in the prostate." in: EMBO reports, Vol. 16, Issue 9, pp. 1219-32, (2015) (PubMed).
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- DGCR8 (DiGeorge Syndrome Critical Region Gene 8 (DGCR8))
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别名
- DGCR8
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背景
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DGCR8 contains 2 DRBM (double-stranded RNA-binding) domains and 1 WW domain. It may play a part in the etiology of the velocardiofacial/DiGeorge syndrome (VCFS/DGS), a developmental disorder characterized by structural and functional palate anomalies, conotruncal cardiac malformations, immunodeficiency, hypocalcemia, and typical facial anomalies.
Alias Symbols: C22orf12, DGCRK6, Gy1, pasha
Protein Interaction Partner: MEOX2, PYCRL, DROSHA, RAE1, MAPK1, PRMT1, ERH, CDKN2A, BMI1, SRPK2, SRPK1, CDT1, NAT10, PLEK2, RPRD2, MAPRE2, PRPF4, FLII, APP, CUL3, DDX17, HNRNPR, NCL, ILF3, HSPA8, HSPA5, HNRNPU, HNRNPH1, FUS, DHX9, DDX5,
Protein Size: 773 -
分子量
- 85 kDa
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基因ID
- 54487
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NCBI登录号
- NM_022720, NP_073557
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UniProt
- Q8WYQ5
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途径
- Regulatory RNA Pathways
抗原
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