TBPL1 抗体 (Middle Region)
Quick Overview for TBPL1 抗体 (Middle Region) (ABIN2776432)
抗原
See all TBPL1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- Middle Region
-
序列
- LQKLGFQVIF TDFKVVNVLA VCNMPFEIRL PEFTKNNRPH ASYEPELHPA
-
预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%
-
产品特性
- This is a rabbit polyclonal antibody against TBPL1. It was validated on Western Blot and immunohistochemistry.
-
纯化方法
- Protein A purified
-
免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human TBPL1
-
-
-
-
应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
-
说明
-
Antigen size: 186 AA
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- Lot specific
-
缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freeze-thaw cycles.
-
储存条件
- -20 °C
-
储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
-
- TBPL1 (TBP-Like 1 (TBPL1))
-
别名
- TBPL1
-
背景
-
Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TBPL1 encodes a protein that serves the same function as TBP and substitutes for TBP at some promoters that are not recognized by TFIID. It is essential for spermiogenesis and believed to be important in expression of developmentally regulated genes.
Alias Symbols: TLF, TLP, STUD, TRF2, MGC:8389, MGC:9620
Protein Interaction Partner: TNNT1, FUS, APP, PRNP, ELAVL1, UBC, TERF2, TERF1, TBPL2, TAF1L, TBP, TAF6, TAF5, TAF4, TAF1, HSPA9, GTF2A2, GTF2A1, SLC35F6, ABCF3, NDUFA6, GTF2B, PTCD3, IRAK4, RAB35, PLIN3, RPL10, NF1, PMVK,
Protein Size: 186 -
分子量
- 21 kDa
-
基因ID
- 9519
-
NCBI登录号
- NM_004865, NP_004856
-
UniProt
- P62380
抗原
-