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KLF6 抗体 (N-Term)

This anti-KLF6 antibody is a 兔 多克隆 antibody detecting KLF6 in WB. Suitable for 人, 小鼠, 大鼠, 犬, 马, 豚鼠, 兔, Cow 和 斑马鱼.
产品编号 ABIN2776378
发货至: 中国

Quick Overview for KLF6 抗体 (N-Term) (ABIN2776378)

抗原

See all KLF6 抗体
KLF6 (Kruppel-Like Factor 6 (KLF6))

适用

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人, 小鼠, 大鼠, 犬, 马, 豚鼠, 兔, Cow, 斑马鱼

宿主

  • 37
  • 5

克隆类型

  • 38
  • 4
多克隆

标记

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This KLF6 antibody is un-conjugated

应用范围

  • 32
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Western Blotting (WB)
  • 抗原表位

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    N-Term

    序列

    REKKEESELK ISSSPPEDTL ISPSFCYNLE TNSLNSDVSS ESSDSSEELS

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 85%

    产品特性

    This is a rabbit polyclonal antibody against KLF6. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human KLF6
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 283 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    KLF6 (Kruppel-Like Factor 6 (KLF6))

    别名

    KLF6

    背景

    KLF6 is a nuclear protein that has three zinc fingers at the end of its C-terminal domain, a serine/threonine-rich central region, and an acidic domain lying within the N-terminal region. The zinc fingers of this protein are responsible for the specific DNA binding with the guanine-rich core promoter elements. The central region might be involved in activation or posttranslational regulatory pathways, and the acidic N-terminal domain might play an important role in the process of transcriptional activation. It is capable of activating transcription approximately 4-fold either on homologous or heterologous promoters. KLF6 may participate in the regulation and/or maintenance of the basal expression of pregnancy-specific glycoprotein genes and possibly other TATA box-less genes.This gene encodes a nuclear protein that has three zinc fingers at the end of its C-terminal domain, a serine/threonine-rich central region, and an acidic domain lying within the N-terminal region. The zinc fingers of this protein are responsible for the specific DNA binding with the guanine-rich core promoter elements. The central region might be involved in activation or posttranslational regulatory pathways, and the acidic N-terminal domain might play an important role in the process of transcriptional activation. It is capable of activating transcription approximately 4-fold either on homologous or heterologous promoters. The DNA binding and transcriptional activity of this protein, in conjunction with its expression pattern, suggests that this protein may participate in the regulation and/or maintenance of the basal expression of pregnancy-specific glycoprotein genes and possibly other TATA box-less genes. Two transcript variants encoding the same protein have been found for this gene. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-731 BM544849.1 20-750 732-1504 BC000311.2 669-1441 1505-1598 BC004301.1 1440-1533
    Alias Symbols: BCD1, COPEB, CPBP, DKFZp686N0199, GBF, PAC1, ST12, ZF9, CBA1
    Protein Interaction Partner: UBC, APP, LCOR, SP1, NUFIP1, NOP56, TAF9, FBL, HDAC3, E2F1, NR0B2, PNO1, POLA2, GTF3C1, EHMT2, APOM, CELSR2, KLF4, TP53, CCND1,
    Protein Size: 283

    分子量

    32 kDa

    基因ID

    1316

    NCBI登录号

    NM_001300, NP_001291

    UniProt

    Q99612
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