GABRE 抗体 (Middle Region)
(3 references)Our Local Distributor
北京 101111
Quick Overview for GABRE 抗体 (Middle Region) (ABIN2776248)
抗原
See all GABRE 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- Middle Region
-
序列
- KNSWKLFQFD FTGVSNKTEI ITTPVGDFMV MTIFFNVSRR FGYVAFQNYV
-
预测反应
- Guinea Pig: 79%, Human: 100%, Mouse: 85%, Rabbit: 86%, Rat: 92%
-
产品特性
- This is a rabbit polyclonal antibody against GABRE. It was validated on Western Blot using a cell lysate as a positive control.
-
纯化方法
- Affinity Purified
-
免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human GABRE
-
-
anti-gamma-aminobutyric Acid (GABA) A Receptor, epsilon (GABRE) (AA 237-286) antibody
GABRE 适用: 人, 小鼠, 豚鼠, 兔, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-gamma-aminobutyric Acid (GABA) A Receptor, epsilon (GABRE) (AA 131-144), (Extracellular) antibodyGABRE 适用: 大鼠 WB, IHC, IC, IF, LCI 宿主: 兔 Polyclonal unconjugated
anti-gamma-aminobutyric Acid (GABA) A Receptor, epsilon (GABRE) (AA 1-100) antibodyGABRE 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1G11 unconjugated
anti-gamma-aminobutyric Acid (GABA) A Receptor, epsilon (GABRE) (AA 35-84) antibodyGABRE 适用: 人, 小鼠, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-gamma-aminobutyric Acid (GABA) A Receptor, epsilon (GABRE) (AA 131-144), (Extracellular) antibody (Atto 633)GABRE 适用: 大鼠 IHC, IC, IF, LCI 宿主: 兔 Polyclonal Atto 633
-
-
应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
-
说明
-
Antigen size: 393 AA
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- Lot specific
-
缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freeze-thaw cycles.
-
储存条件
- -20 °C
-
储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
-
-
: "Expression of GABAA ?2-, ?1- and ?-receptors are altered significantly in the lateral cerebellum of subjects with schizophrenia, major depression and bipolar disorder." in: Translational psychiatry, Vol. 3, pp. e303, (2013) (PubMed).
: "Increased GABA(A) receptor ?-subunit expression on ventral respiratory column neurons protects breathing during pregnancy." in: PLoS ONE, Vol. 7, Issue 1, pp. e30608, (2012) (PubMed).
: "Changes in ventral respiratory column GABAaR ?- and ?-subunits during hibernation mediate resistance to depression by EtOH and pentobarbital." in: American journal of physiology. Regulatory, integrative and comparative physiology, Vol. 300, Issue 2, pp. R272-83, (2011) (PubMed).
-
: "Expression of GABAA ?2-, ?1- and ?-receptors are altered significantly in the lateral cerebellum of subjects with schizophrenia, major depression and bipolar disorder." in: Translational psychiatry, Vol. 3, pp. e303, (2013) (PubMed).
-
- GABRE (gamma-aminobutyric Acid (GABA) A Receptor, epsilon (GABRE))
-
别名
- GABRE
-
背景
-
GABRE belongs to the ligand-gated ionic channel (TC 1.A.9) family. It encodes the gamma-aminobutyric acid (GABA) A receptor which is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. This gene encodes an epsilon subunit. It is mapped to chromosome Xq28 in a cluster comprised of genes encoding alpha 3, beta 4 and theta subunits of the same receptor. Alternatively spliced transcript variants encoding different isoforms have been identified.
Protein Size: 393 -
分子量
- 43 kDa
-
基因ID
- 2564
-
NCBI登录号
- NM_021984, NP_068819
-
途径
- Synaptic Membrane
抗原
-
