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GABRQ 抗体 (N-Term)

Cited in 1 publication. This 兔 多克隆 anti-GABRQ antibody specifically detects GABRQ in WB. The antibody is reactive with 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 兔, 马 和 Pig samples.
产品编号 ABIN2776224
发货至: 中国
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Quick Overview for GABRQ 抗体 (N-Term) (ABIN2776224)

抗原

See all GABRQ 抗体
GABRQ (gamma-aminobutyric Acid (GABA) Receptor, theta (GABRQ))

适用

人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 兔, 马, Pig

宿主

  • 29
  • 1

克隆类型

  • 29
  • 1
多克隆

标记

  • 11
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This GABRQ antibody is un-conjugated

应用范围

  • 13
  • 13
  • 9
  • 9
  • 4
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB)
  • 抗原表位

    • 15
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    N-Term

    序列

    KFHFEFSSAV PEVVLNLFNC KNCANEAVVQ KILDRVLSRY DVRLRPNFGG

    预测反应

    Cow: 87%, Dog: 87%, Guinea Pig: 80%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 100%, Rat: 100%

    产品特性

    This is a rabbit polyclonal antibody against GABRQ. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human GABRQ
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 632 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Fatemi, Folsom, Rooney, Thuras: "mRNA and protein expression for novel GABAA receptors ? and ?2 are altered in schizophrenia and mood disorders; relevance to FMRP-mGluR5 signaling pathway." in: Translational psychiatry, Vol. 3, pp. e271, (2013) (PubMed).

  • 抗原

    GABRQ (gamma-aminobutyric Acid (GABA) Receptor, theta (GABRQ))

    别名

    GABRQ

    背景

    The gamma-aminobutyric acid (GABA) A receptor is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. This gene encodes GABA A receptor, theta subunit. GABRQ gene is mapped to chromosome Xq28 in a cluster including the genes encoding the alpha 3 and epsilon subunits of the same receptor. This gene location is also the candidate region of 2 different neurologic diseases:early-onset parkinsonism (Waisman syndrome) and X-linked mental retardation (MRX3).The gamma-aminobutyric acid (GABA) A receptor is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. This gene encodes GABA A receptor, theta subunit. It is mapped to chromosome Xq28 in a cluster including the genes encoding the alpha 3 and epsilon subunits of the same receptor. This gene location is also the candidate region of 2 different neurologic diseases: early-onset parkinsonism (Waisman syndrome) and X-linked mental retardation (MRX3).
    Alias Symbols: THETA
    Protein Size: 632

    分子量

    72 kDa

    基因ID

    55879

    NCBI登录号

    NM_018558, NP_061028

    UniProt

    Q9UN88
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